Detailed information NTG0552954

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: J7U23_RS09800
• Genome accession: NZ_CP072435
• Coordinates: 1893636..1894871 (+)
• Length: 411 a.a.
• NCBI ID: WP_372589919.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24736
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1888636..1899871

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U23_RS09770 (J7U23_09695)	-	1889102..1891708 (+)	2607	WP_179971113.1	YfhO family protein	-
J7U23_RS09790 (J7U23_09715)	-	1892253..1892936 (-)	684	WP_164178359.1	YoaK family protein	-
J7U23_RS09795 (J7U23_09720)	rlmH	1892952..1893431 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
J7U23_RS09800 (J7U23_09725)	htrA	1893636..1894871 (+)	1236	WP_372589919.1	S1C family serine protease	Regulator
J7U23_RS09805 (J7U23_09730)	spo0J	1894937..1895704 (+)	768	WP_180477211.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42844.11 Da
• Isoelectric Point: 4.7654

>NTDB_id=552954 J7U23_RS09800 WP_372589919.1 1893636..1894871(+) (htrA) [Streptococcus thermophilus strain S24736]
MKKFNWKKIVAPIAILIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGNSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKLSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRSALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=552954 J7U23_RS09800 WP_372589919.1 1893636..1894871(+) (htrA) [Streptococcus thermophilus strain S24736]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATACTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGAACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAATTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGATCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (308-402)

• Peptidase family M50 (Peptidase_M50) (4-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.611	100	0.596
htrA	Streptococcus gordonii str. Challis substr. CH1	56.553	100	0.567
htrA	Streptococcus mitis NCTC 12261	53.056	99.513	0.528
htrA	Streptococcus pneumoniae TIGR4	52.812	99.513	0.526
htrA	Streptococcus pneumoniae D39	52.812	99.513	0.526
htrA	Streptococcus pneumoniae Rx1	52.812	99.513	0.526
htrA	Streptococcus pneumoniae R6	52.812	99.513	0.526