Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   J7U22_RS01640 Genome accession   NZ_CP072428
Coordinates   311340..312035 (+) Length   231 a.a.
NCBI ID   WP_014608614.1    Uniprot ID   A0AAU9H5B0
Organism   Streptococcus thermophilus strain S24749     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 306340..317035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS01615 (J7U22_01610) - 308399..308668 (-) 270 WP_260222877.1 GIY-YIG nuclease family protein -
  J7U22_RS01620 (J7U22_01615) - 308672..309436 (-) 765 WP_260222876.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  J7U22_RS01625 - 309486..309635 (-) 150 WP_014608616.1 polysaccharide deacetylase -
  J7U22_RS01630 - 309744..310277 (-) 534 WP_014608615.1 polysaccharide deacetylase family protein -
  J7U22_RS01635 (J7U22_01625) - 310477..311232 (+) 756 WP_002948862.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  J7U22_RS01640 (J7U22_01630) comEA 311340..312035 (+) 696 WP_014608614.1 helix-hairpin-helix domain-containing protein Machinery gene
  J7U22_RS01645 (J7U22_01635) - 312025..314265 (+) 2241 WP_372588849.1 DNA internalization-related competence protein ComEC/Rec2 -
  J7U22_RS01650 (J7U22_01640) - 314351..315613 (+) 1263 WP_022096991.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  J7U22_RS01655 (J7U22_01645) - 315679..316224 (+) 546 WP_260214683.1 GNAT family N-acetyltransferase -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24602.52 Da        Isoelectric Point: 4.5661

>NTDB_id=552560 J7U22_RS01640 WP_014608614.1 311340..312035(+) (comEA) [Streptococcus thermophilus strain S24749]
MKEKILAYVKDNRLFVSVIAVLMVIFCFFLWMTCGAGNSMEAETSYTDVTALSTSSSKQSSQSLSEASSQSKTEGSEKVK
SKVTVDVKGAVVNPGVYTLKEGARVTDVIQEAGGMTEDADAKSVNLAASLSDEEVIYVANKDENVSVLDQTSTGQVSDKG
GQAVSKDGKINLNTATSEQLQTISGIGAKRTEDIIAYRESHGGFQSVDDLKNVSGIGDKTLDKIRESLYVA

Nucleotide


Download         Length: 696 bp        

>NTDB_id=552560 J7U22_RS01640 WP_014608614.1 311340..312035(+) (comEA) [Streptococcus thermophilus strain S24749]
GTGAAGGAAAAGATTCTAGCCTATGTCAAAGATAATCGTCTGTTTGTGAGTGTCATCGCTGTACTGATGGTGATTTTTTG
CTTCTTTTTATGGATGACTTGTGGTGCCGGCAACAGCATGGAGGCGGAGACGTCTTATACAGATGTGACAGCTTTGTCAA
CGTCTTCATCCAAACAAAGTTCACAGTCTCTTTCTGAGGCGTCTTCCCAGTCAAAGACCGAAGGAAGTGAAAAAGTTAAG
TCAAAAGTAACGGTAGATGTTAAGGGGGCTGTGGTCAATCCAGGTGTCTATACGCTAAAGGAAGGCGCTAGGGTGACAGA
TGTCATTCAGGAAGCTGGAGGAATGACAGAAGATGCAGACGCTAAGAGTGTTAACTTAGCCGCAAGCTTGTCAGATGAAG
AGGTTATTTATGTAGCCAATAAAGATGAAAATGTTTCTGTCCTTGATCAAACAAGTACTGGTCAGGTCTCTGATAAAGGA
GGGCAGGCTGTATCTAAGGATGGTAAAATTAACTTAAATACAGCAACCTCAGAGCAGTTGCAAACCATTTCTGGAATTGG
AGCTAAGCGGACAGAGGATATCATTGCCTATCGTGAAAGTCATGGCGGCTTTCAGTCCGTAGATGACTTGAAAAATGTCT
CAGGAATTGGTGATAAAACATTAGATAAAATCAGAGAGTCCCTCTATGTGGCTTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(167-228)

SLBB domain (SLBB)

(85-138)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

98.268

100

0.983
  comEA/celA/cilE Streptococcus mitis SK321

40.175

99.134

0.398
  comEA/celA/cilE Streptococcus pneumoniae D39

38.596

98.701

0.381
  comEA/celA/cilE Streptococcus pneumoniae R6

38.596

98.701

0.381
  comEA/celA/cilE Streptococcus pneumoniae Rx1

38.596

98.701

0.381
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

38.596

98.701

0.381
  comEA/celA/cilE Streptococcus mitis NCTC 12261

37.281

98.701

0.368