Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   J4854_RS07650 Genome accession   NZ_CP072329
Coordinates   1524480..1525181 (-) Length   233 a.a.
NCBI ID   WP_200772623.1    Uniprot ID   A0A9X0WN49
Organism   Streptococcus lactarius strain CCUG 66490     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1519480..1530181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS07625 (J4854_07625) - 1519853..1520392 (-) 540 WP_200772626.1 DUF3592 domain-containing protein -
  J4854_RS07630 (J4854_07630) - 1520393..1521442 (-) 1050 WP_234700091.1 hypothetical protein -
  J4854_RS07635 (J4854_07635) - 1521646..1522173 (-) 528 WP_200772625.1 hypothetical protein -
  J4854_RS07640 (J4854_07640) vicX 1522315..1523124 (-) 810 WP_200772624.1 MBL fold metallo-hydrolase Regulator
  J4854_RS07645 (J4854_07645) micB 1523132..1524487 (-) 1356 WP_187540437.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J4854_RS07650 (J4854_07650) micA 1524480..1525181 (-) 702 WP_200772623.1 response regulator YycF Regulator
  J4854_RS07655 (J4854_07655) - 1525686..1526735 (+) 1050 WP_200772622.1 DUF389 domain-containing protein -
  J4854_RS07660 (J4854_07660) thrS 1526947..1528890 (-) 1944 WP_200772621.1 threonine--tRNA ligase -
  J4854_RS07665 (J4854_07665) - 1528959..1529104 (-) 146 Protein_1473 AAA family ATPase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26682.43 Da        Isoelectric Point: 4.5983

>NTDB_id=552059 J4854_RS07650 WP_200772623.1 1524480..1525181(-) (micA) [Streptococcus lactarius strain CCUG 66490]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDIIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADSQLENDADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLSTHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=552059 J4854_RS07650 WP_200772623.1 1524480..1525181(-) (micA) [Streptococcus lactarius strain CCUG 66490]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCGATTTCAGATATTATTAAATTCAACATGGCGAAAGAAGGCTATGA
AGTCTTGACGGCTTTTGATGGTCGGGAAGCCTTGGAAGTTTTTGCGGCTGAAAATCCAGATATTATTATTTTGGACTTGA
TGTTGCCAGAGATTGATGGTTTGGAAGTGGCGCGTACGATTCGCAAGACCAGCAATGTGCCGATTATTGTCCTTTCTGCC
AAGGATACGGAGTTTGATAAGGTCATCGGTCTTGAGATTGGGGCAGATGACTACGTGACTAAGCCGTTCTCAAATCGTGA
ATTGCAGGCGCGTGTGAAGGCCTTGTTGCGCCGTTCTGAATTTGCTGCGGATTCTCAGCTTGAAAATGATGCCGACACTG
AGATTGTCATTGGAGATCTTCACATTCTTCCAGATGCTTTCTTGGTTCAAAAAGGCAATAAAGAATTGGATCTAACCCAT
CGGGAGTTTGAATTGCTCTATCACTTGTCGACCCATGTTGGACAAGTGATGACACGGGAGCATCTTCTTGAAACCGTTTG
GGGCTATGATTACTTTGGAGATGTTCGGACAGTGGACGTGACGGTTCGTCGCTTGCGTGAAAAAATCGAAGACACACCAG
GACGTCCTGAGTATATCTTGACCCGCCGTGGTGTCGGGTATTACATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

100

0.82
  vicR Streptococcus mutans UA159

77.872

100

0.785
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429