Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   J4854_RS07645 Genome accession   NZ_CP072329
Coordinates   1523132..1524487 (-) Length   451 a.a.
NCBI ID   WP_187540437.1    Uniprot ID   -
Organism   Streptococcus lactarius strain CCUG 66490     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1518132..1529487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS07615 (J4854_07615) rnc 1518588..1519289 (-) 702 WP_200772628.1 ribonuclease III -
  J4854_RS07620 (J4854_07620) - 1519390..1519776 (-) 387 WP_200772627.1 YbaN family protein -
  J4854_RS07625 (J4854_07625) - 1519853..1520392 (-) 540 WP_200772626.1 DUF3592 domain-containing protein -
  J4854_RS07630 (J4854_07630) - 1520393..1521442 (-) 1050 WP_234700091.1 hypothetical protein -
  J4854_RS07635 (J4854_07635) - 1521646..1522173 (-) 528 WP_200772625.1 hypothetical protein -
  J4854_RS07640 (J4854_07640) vicX 1522315..1523124 (-) 810 WP_200772624.1 MBL fold metallo-hydrolase Regulator
  J4854_RS07645 (J4854_07645) micB 1523132..1524487 (-) 1356 WP_187540437.1 cell wall metabolism sensor histidine kinase VicK Regulator
  J4854_RS07650 (J4854_07650) micA 1524480..1525181 (-) 702 WP_200772623.1 response regulator YycF Regulator
  J4854_RS07655 (J4854_07655) - 1525686..1526735 (+) 1050 WP_200772622.1 DUF389 domain-containing protein -
  J4854_RS07660 (J4854_07660) thrS 1526947..1528890 (-) 1944 WP_200772621.1 threonine--tRNA ligase -
  J4854_RS07665 (J4854_07665) - 1528959..1529104 (-) 146 Protein_1473 AAA family ATPase -

Sequence

Protein


Download         Length: 451 a.a.        Molecular weight: 51393.63 Da        Isoelectric Point: 4.5672

>NTDB_id=552058 J4854_RS07645 WP_187540437.1 1523132..1524487(-) (micB) [Streptococcus lactarius strain CCUG 66490]
MIDQLKQFVMSSNFVFVLITIGFMIVVALFLLENRKDNVKLRQLNAKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNIHPEEVLNTSILDLLSIGQDYDLRTLITEVPE
LTIDSQDENGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGAIF
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLEIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNLLNNAIKYSPDGGTIRVGMKTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDDWDSEEEE

Nucleotide


Download         Length: 1356 bp        

>NTDB_id=552058 J4854_RS07645 WP_187540437.1 1523132..1524487(-) (micB) [Streptococcus lactarius strain CCUG 66490]
ATGATTGATCAATTAAAACAATTTGTTATGTCGTCAAACTTTGTGTTTGTCCTGATTACGATTGGTTTTATGATCGTCGT
AGCCTTGTTCTTACTGGAGAACCGCAAGGACAATGTAAAGTTGAGGCAACTAAATGCCAAAATTAAGGATTTGATCGCAG
GGGACTATTCCGAAGTTGTTGACATGCAAGGAAGCCCAGAATTGACCGATATGACTAATAGTATCAATGATTTGTCAGAG
GTGATTCGGCTCACGCATGAAAACTTGGAGCAGGAAACCAAGCGCTTGACCAGTATCCTTTCTTATATGACAGATGGGGT
GCTTGCGACCAATCGTCGTGGGCAGATCATTATGGTCAATGAAATGGCTGCCAAGCAATTAAATATTCATCCAGAAGAAG
TCTTGAATACGAGTATTTTGGATTTGCTCTCGATTGGGCAGGACTATGATCTGCGAACCTTGATTACCGAAGTGCCTGAG
TTGACCATCGATTCTCAGGATGAAAATGGGGAATATTTGAGCTTGCGTGTACGGTTTGCTTTGATTCGTCGGGAATCAGG
ATTTATCTCTGGTCTAGTAGCGGTCTTGCATGACACGACAGAGCAGGACAAGGAAGAACGTGAACGGCGTCTCTTTGTCT
CCAATGTCAGCCATGAATTGCGGACCCCATTGACCAGTGTCAAATCATACTTGGAAGCCTTGGACGATGGAGCTATATTT
GAGCCCGTTGCACCGGACTTTGTCAAGGTTTCGCTCAATGAAACAAACCGGATGATGCGGATGGTGACAGACCTTTTGAG
TCTGTCTCGCATTGACAACGAAACCAGTCAATTGGAGATTGAGTTAACTAACTTTACAGCCTTTATCACCTTTATTTTGA
ACCGATTTGACAAGATCAAGAGTCAATCGCAAGAGGATACCAAAAAGTATGAACTCATTCGAGAGTATCCAATTACACCG
ATCTGGGTCGAAATTGATACTGACAAAATGACGCAGGTGATCGACAATCTCTTGAATAATGCGATCAAGTATTCACCGGA
TGGTGGGACGATTAGAGTCGGGATGAAAACGACAGATGCTCAGTTGATTATTTCCATCTCTGATGAGGGATTGGGAATTC
CAAAGAAAGATTTGCCTCGTATTTTTGACCGCTTTTATCGAGTGGATAAGGCGCGCAGCCGGGCTCAAGGTGGAACTGGT
CTAGGCCTAGCCATTGCGAAAGAAATCATCAAGCAGCACAAGGGCTTTATTTGGGCCAAGAGTGAGTATGGCAAGGGCTC
GACCTTTACCATTGTCTTGCCATATGACAAGGATGCGATCAAAGACGATGACTGGGATTCAGAAGAGGAAGAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

77.778

97.783

0.761
  vicK Streptococcus mutans UA159

70.025

90.244

0.632