Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   J4854_RS04505 Genome accession   NZ_CP072329
Coordinates   864621..865301 (+) Length   226 a.a.
NCBI ID   WP_200771978.1    Uniprot ID   A0A9X0WLY8
Organism   Streptococcus lactarius strain CCUG 66490     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 859621..870301
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS04480 (J4854_04480) - 860581..861291 (-) 711 WP_200771982.1 LytR/AlgR family response regulator transcription factor -
  J4854_RS04485 (J4854_04485) - 861398..862354 (+) 957 WP_200772070.1 ABC transporter ATP-binding protein -
  J4854_RS04490 (J4854_04490) - 862356..863078 (+) 723 WP_200771981.1 ABC transporter permease -
  J4854_RS04495 (J4854_04495) - 863223..863756 (-) 534 WP_200771980.1 biotin transporter BioY -
  J4854_RS04500 (J4854_04500) - 863962..864486 (+) 525 WP_200771979.1 hypothetical protein -
  J4854_RS04505 (J4854_04505) ciaR 864621..865301 (+) 681 WP_200771978.1 response regulator transcription factor Regulator
  J4854_RS04510 (J4854_04510) ciaH 865285..866655 (+) 1371 WP_200771977.1 sensor histidine kinase Regulator
  J4854_RS04515 (J4854_04515) - 866655..867035 (+) 381 WP_200771976.1 VOC family protein -
  J4854_RS04520 (J4854_04520) - 867284..868666 (+) 1383 WP_200771975.1 polysaccharide deacetylase family protein -
  J4854_RS04525 (J4854_04525) - 868991..870076 (-) 1086 WP_200771974.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 25837.60 Da        Isoelectric Point: 4.3321

>NTDB_id=552051 J4854_RS04505 WP_200771978.1 864621..865301(+) (ciaR) [Streptococcus lactarius strain CCUG 66490]
MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGIYDLILLDLMLPEKDGFHVLKELREKGVTTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKVNENTLNYGNLKVNLSTNSTYIDDKEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKGTDFVENLQTLRSVGYILKDVNKD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=552051 J4854_RS04505 WP_200771978.1 864621..865301(+) (ciaR) [Streptococcus lactarius strain CCUG 66490]
ATGATTAAAATTCTATTGGTCGAAGATGACCTTGGTTTATCAAATTCAGTATTTGATTTTTTAGATGATTTTGCGGACGT
TATGCAGGTCTTTGACGGAGAAGAAGGTCTTTACGAAGCAGAAAGCGGGATCTATGATTTGATTCTGCTGGACCTCATGC
TTCCTGAAAAAGACGGTTTCCATGTCTTGAAAGAACTGCGTGAAAAAGGCGTGACGACTCCTGTCTTGATTATGACAGCC
AAAGAAAGTCTGGATGACAAAGGACATGGTTTTGAGCTAGGGGCAGACGATTACCTCACCAAGCCTTTCTATCTTGAAGA
GCTTAAGATGCGGATTCAAGCTCTCTTGAAGCGCTCAGGTAAGGTCAATGAAAACACCCTCAATTATGGCAATTTGAAGG
TGAATTTATCTACCAATTCGACTTATATCGATGACAAAGAAGTTGAATTACTCGGAAAAGAGTTTGATCTCTTAGTTTAC
TTCCTTCAAAACCAAAATGTCATTCTCCCTAAAACGCAAATTTTCGACCGTTTGTGGGGGTTTGACAGCGATACCACCAT
TTCAGTTGTTGAAGTGTATGTATCGAAAATTCGTAAAAAATTAAAAGGAACGGATTTCGTAGAAAACTTACAAACATTGC
GTAGTGTGGGGTATATCTTAAAAGATGTTAACAAGGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

91.071

99.115

0.903
  ciaR Streptococcus pneumoniae D39

91.071

99.115

0.903
  ciaR Streptococcus pneumoniae R6

91.071

99.115

0.903
  ciaR Streptococcus pneumoniae TIGR4

91.071

99.115

0.903
  ciaR Streptococcus mutans UA159

87.5

99.115

0.867
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.445

100

0.376
  vicR Streptococcus mutans UA159

36.052

100

0.372