Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   J4854_RS04510 Genome accession   NZ_CP072329
Coordinates   865285..866655 (+) Length   456 a.a.
NCBI ID   WP_200771977.1    Uniprot ID   A0A9X0WMI2
Organism   Streptococcus lactarius strain CCUG 66490     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 860285..871655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J4854_RS04480 (J4854_04480) - 860581..861291 (-) 711 WP_200771982.1 LytR/AlgR family response regulator transcription factor -
  J4854_RS04485 (J4854_04485) - 861398..862354 (+) 957 WP_200772070.1 ABC transporter ATP-binding protein -
  J4854_RS04490 (J4854_04490) - 862356..863078 (+) 723 WP_200771981.1 ABC transporter permease -
  J4854_RS04495 (J4854_04495) - 863223..863756 (-) 534 WP_200771980.1 biotin transporter BioY -
  J4854_RS04500 (J4854_04500) - 863962..864486 (+) 525 WP_200771979.1 hypothetical protein -
  J4854_RS04505 (J4854_04505) ciaR 864621..865301 (+) 681 WP_200771978.1 response regulator transcription factor Regulator
  J4854_RS04510 (J4854_04510) ciaH 865285..866655 (+) 1371 WP_200771977.1 sensor histidine kinase Regulator
  J4854_RS04515 (J4854_04515) - 866655..867035 (+) 381 WP_200771976.1 VOC family protein -
  J4854_RS04520 (J4854_04520) - 867284..868666 (+) 1383 WP_200771975.1 polysaccharide deacetylase family protein -
  J4854_RS04525 (J4854_04525) - 868991..870076 (-) 1086 WP_200771974.1 DEAD/DEAH box helicase -
  J4854_RS04530 (J4854_04530) - 870073..871053 (-) 981 WP_200771973.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 456 a.a.        Molecular weight: 52049.65 Da        Isoelectric Point: 9.3266

>NTDB_id=552052 J4854_RS04510 WP_200771977.1 865285..866655(+) (ciaH) [Streptococcus lactarius strain CCUG 66490]
MLTRIKKTVGEDDFSYFIRYFGLFTLIFSAMTLIIIQVMRSSLYTTVDENLKTLSQDPYSIVAIANRDQRQSGDKLNDKE
NDVMDVPNHDKSEPKGDVTSNTTVVLLNKKYENLTTGNGFLNLKSVIFGRKLLNKVSQLRITNSYGKKESYRAYMTDLGL
SDGDESDVKYAVIMTNISQLEQTSEKNESQIALVMICFWGISLFASLFLARLSVKPLLESMQKQKAFVENASHELRTPLA
VLQNRLETLFRKPEATIMESSESIASSLDEVRNMKLLTTNLLNIARRDDGLKPEIDEIDPSFFDQTFSNFEIIAEENAKV
FRGENRVDKIISSDKILLKQLMTILYDNALKYTDEDGEIGFKVQLKDKNLLIKVLDNGPGIPDEDKKRIFDRFYRVDKAR
TRQKGGFGLGLSLAKQIVEAFKGNIQVRDNKPRGTIFEVKLSTKTESRKRNRKEEK

Nucleotide


Download         Length: 1371 bp        

>NTDB_id=552052 J4854_RS04510 WP_200771977.1 865285..866655(+) (ciaH) [Streptococcus lactarius strain CCUG 66490]
ATGTTAACAAGGATTAAGAAAACCGTCGGAGAAGATGACTTTTCCTATTTCATCCGCTATTTTGGCCTTTTTACCCTGAT
TTTCTCAGCCATGACCTTGATCATTATTCAGGTCATGCGCTCGAGCCTTTATACGACGGTCGATGAGAACCTCAAGACTC
TTAGCCAAGATCCTTATTCGATTGTGGCCATTGCCAATCGCGACCAAAGGCAATCGGGTGACAAGCTAAATGATAAAGAG
AACGATGTCATGGATGTCCCAAATCATGATAAGTCAGAGCCCAAAGGAGATGTCACCTCCAATACAACGGTCGTTCTTCT
CAATAAAAAATATGAAAATCTGACAACTGGAAATGGATTTCTAAACCTCAAATCTGTAATCTTTGGACGCAAACTGCTTA
ACAAGGTTTCACAGCTCCGGATTACCAATAGCTATGGTAAAAAAGAAAGTTACCGGGCCTATATGACGGATCTGGGCTTA
TCAGATGGTGATGAGAGTGATGTCAAATACGCGGTCATCATGACCAATATTAGCCAGTTGGAGCAGACGAGCGAAAAGAA
TGAGAGCCAAATTGCCCTCGTTATGATCTGCTTCTGGGGGATTTCACTGTTTGCAAGTCTCTTTCTGGCTCGTCTTAGTG
TCAAGCCACTTCTTGAGAGCATGCAAAAGCAAAAAGCCTTTGTGGAAAATGCCTCACATGAATTGCGGACGCCCCTTGCA
GTTCTACAAAATCGTTTAGAAACACTTTTTAGAAAACCAGAAGCAACCATTATGGAATCGAGCGAGAGCATTGCCTCAAG
TCTAGATGAGGTCCGAAATATGAAGCTCTTGACCACCAACCTGCTCAACATTGCCCGAAGGGATGATGGCTTGAAGCCAG
AGATCGATGAGATTGACCCTAGCTTCTTTGATCAGACCTTCTCAAATTTTGAGATTATCGCAGAAGAAAATGCCAAGGTC
TTTCGAGGCGAGAACCGAGTCGACAAGATCATTTCATCAGATAAAATCCTGCTCAAGCAGTTGATGACCATCTTGTATGA
CAATGCCTTGAAATATACAGATGAGGATGGTGAAATTGGCTTTAAAGTTCAATTGAAGGACAAAAATCTCCTTATCAAAG
TTCTGGATAATGGACCTGGTATTCCCGATGAAGACAAAAAGCGGATTTTTGATCGCTTTTATCGGGTGGACAAGGCTAGA
ACCCGTCAAAAAGGTGGATTTGGCCTAGGCTTATCGCTTGCCAAACAAATCGTAGAAGCCTTTAAAGGAAACATTCAAGT
CAGAGATAACAAACCAAGAGGAACCATCTTTGAAGTGAAATTATCTACAAAAACAGAAAGTCGTAAAAGAAATCGAAAAG
AGGAAAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(225-290)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(334-442)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.089

98.904

0.594
  ciaH Streptococcus pneumoniae D39

60.089

98.904

0.594
  ciaH Streptococcus pneumoniae R6

60.089

98.904

0.594
  ciaH Streptococcus pneumoniae TIGR4

60.089

98.904

0.594
  ciaH Streptococcus mutans UA159

50.901

97.368

0.496