Detailed information NTG0552011

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: J4854_RS00010
• Genome accession: NZ_CP072329
• Coordinates: 244..1425 (+)
• Length: 393 a.a.
• NCBI ID: WP_200772344.1
• Uniprot ID: -
• Organism: Streptococcus lactarius strain CCUG 66490
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1..6425

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4854_RS00010 (J4854_00010)	htrA	244..1425 (+)	1182	WP_200772344.1	S1C family serine protease	Regulator
J4854_RS00015 (J4854_00015)	spo0J	1497..2258 (+)	762	WP_187538550.1	ParB/RepB/Spo0J family partition protein	Regulator
J4854_RS00020 (J4854_00020)	dnaA	2524..3882 (+)	1359	WP_200772343.1	chromosomal replication initiator protein DnaA	-
J4854_RS00025 (J4854_00025)	dnaN	4042..5178 (+)	1137	WP_200772342.1	DNA polymerase III subunit beta	-
J4854_RS00030 (J4854_00030)	-	5190..5381 (+)	192	WP_200772341.1	DUF951 domain-containing protein	-
J4854_RS00035 (J4854_00035)	-	5417..5914 (-)	498	WP_200772340.1	DUF1307 domain-containing protein	-

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 41694.82 Da
• Isoelectric Point: 5.4540

>NTDB_id=552011 J4854_RS00010 WP_200772344.1 244..1425(+) (htrA) [Streptococcus lactarius strain CCUG 66490]
MKSSSHLLKKIGTLSLIFVVGFLGGILGTVLTLQVSHSSNATTESKQVRSTTVKTAYKNTTSTSQAVDKVKNAVVSVITY
ADSSNQDLFTNDEHSDSQISSEGSGVIYKKDGKYAYLVTNTHVISGAKKVDILLADGNKVPGEVVGSDVYSDIAVVRISA
DKAKDVAEFGDSNQLTVGETAIAIGSPLGTDYANSVTQGIISSQGRNVNLKADNGQNISTRALQTDAAINPGNSGGPLIN
IQGQVIGITSSKISTNGQTSVEGMGFAIPANDVVNIIKQLEENGKVVRPALGIQMMDLANLSTSDLSKLKLPEKISGGVI
VRSTLDNMPASDKLQRYDVITKIDDTDIESTADLQSALYSHQIDDTIKVTFYRDGKQETTTIKLTKSTEDLEK

Nucleotide

• Length: 1182 bp

>NTDB_id=552011 J4854_RS00010 WP_200772344.1 244..1425(+) (htrA) [Streptococcus lactarius strain CCUG 66490]
ATGAAATCTTCATCCCATTTACTAAAAAAAATTGGGACTTTATCCCTCATTTTTGTAGTCGGTTTTCTTGGTGGGATTCT
TGGAACAGTTTTAACATTACAAGTATCTCATTCATCAAATGCAACGACTGAAAGCAAACAAGTACGCTCCACTACTGTAA
AGACAGCATATAAAAATACAACCTCAACGAGCCAAGCTGTTGATAAAGTAAAAAATGCAGTGGTATCTGTAATCACCTAT
GCAGATTCTTCAAATCAAGATTTATTTACAAATGATGAACATTCAGATTCTCAAATCTCCAGTGAAGGATCGGGAGTGAT
TTATAAAAAAGATGGAAAATATGCCTATCTTGTGACCAATACCCATGTTATTAGTGGTGCTAAAAAAGTAGATATCTTAT
TAGCGGATGGCAATAAAGTTCCTGGAGAAGTTGTTGGTTCCGATGTCTATTCTGATATTGCTGTTGTCAGAATTAGTGCA
GATAAAGCCAAAGATGTCGCTGAATTTGGGGATTCAAACCAGTTAACTGTTGGTGAGACTGCTATAGCTATTGGAAGCCC
CCTAGGGACGGATTATGCAAACTCTGTTACCCAAGGAATTATTTCAAGTCAAGGTCGAAATGTTAATTTAAAAGCTGACA
ATGGACAAAATATCTCTACACGTGCCTTGCAAACAGATGCTGCTATCAATCCAGGTAACTCAGGAGGACCTTTGATCAAC
ATCCAAGGACAGGTCATTGGAATTACCTCAAGCAAAATTTCAACGAATGGACAGACTTCTGTAGAAGGAATGGGATTTGC
AATTCCTGCAAACGATGTTGTCAATATTATCAAACAATTGGAAGAAAACGGAAAGGTCGTTCGACCAGCGCTTGGAATCC
AAATGATGGACCTTGCAAATCTTTCAACTTCTGATTTGAGTAAATTAAAACTTCCTGAAAAAATCTCCGGAGGAGTCATT
GTTCGCTCAACACTTGACAATATGCCTGCATCGGATAAATTGCAACGTTACGATGTCATTACTAAAATTGACGATACAGA
CATTGAGTCAACTGCAGATTTACAATCTGCTCTCTATTCTCACCAAATTGACGATACCATTAAGGTAACCTTCTATCGAG
ATGGAAAACAAGAGACAACTACTATTAAGTTGACAAAATCAACAGAAGATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (289-384)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	65.823	100	0.662
htrA	Streptococcus pneumoniae Rx1	63.959	100	0.641
htrA	Streptococcus pneumoniae D39	63.959	100	0.641
htrA	Streptococcus pneumoniae R6	63.959	100	0.641
htrA	Streptococcus pneumoniae TIGR4	63.959	100	0.641
htrA	Streptococcus mitis NCTC 12261	63.706	100	0.639
htrA	Streptococcus mutans UA159	52.85	98.219	0.519