Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   ANG_RS08155 Genome accession   NZ_AP013072
Coordinates   1621240..1623390 (-) Length   716 a.a.
NCBI ID   WP_025271907.1    Uniprot ID   -
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1616240..1628390
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS11505 - 1616337..1616405 (-) 69 Protein_1603 bacteriocin class II family protein -
  ANG_RS08130 (ANG_1653) - 1616637..1617350 (+) 714 WP_003037434.1 CPBP family intramembrane glutamic endopeptidase -
  ANG_RS08135 (ANG_1654) comE/blpR 1617519..1618265 (+) 747 WP_025271905.1 response regulator transcription factor Regulator
  ANG_RS11510 comD/blpH 1618756..1619577 (+) 822 WP_231847271.1 sensor histidine kinase Regulator
  ANG_RS08145 (ANG_1656) - 1619622..1619771 (-) 150 WP_003037249.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ANG_RS08150 (ANG_1657) - 1619868..1621229 (-) 1362 WP_003037280.1 bacteriocin secretion accessory protein -
  ANG_RS08155 (ANG_1658) comA/nlmT 1621240..1623390 (-) 2151 WP_025271907.1 peptide cleavage/export ABC transporter Regulator
  ANG_RS08160 (ANG_1660) - 1623871..1624245 (+) 375 WP_003037526.1 hypothetical protein -
  ANG_RS08175 (ANG_1663) - 1625760..1626365 (-) 606 WP_003034324.1 superoxide dismutase -
  ANG_RS08180 (ANG_1664) holA 1626436..1627473 (-) 1038 WP_003034316.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80255.74 Da        Isoelectric Point: 9.4610

>NTDB_id=55129 ANG_RS08155 WP_025271907.1 1621240..1623390(-) (comA/nlmT) [Streptococcus anginosus subsp. whileyi MAS624]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKEQFTKEWTGVAIFLAPKPSYKPHKDKKNGLASFLPLI
FKQRSLIFYIVLASLLVTLINIVGSYYLQSVLDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLLLDLSILIIVGSVLLLQNANLFLLTLLAIPIYALI
IFAFMKPFEKMNNDVMQSNAMVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLDKTFKLSKYSIVQTALKQGAQFV
LNVVILWVGASLVMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANHRLNEIYLVESEFKTKQVLTEKNFLA
GDITFHNVSYKYGFGRDTLSDISLTIKKGDKISLFGISGSGKTTLAKMIVHFYEPYQGQIRLNGNDLKTIDKKVLRQYIN
YLPQQAYIFSGSILDNLTLGADQTVSQSDILRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMKLPDKTIIFVAHRLSISKRTNQIIVLDQGKVIETGSHTELIERKGFYYHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=55129 ANG_RS08155 WP_025271907.1 1621240..1623390(-) (comA/nlmT) [Streptococcus anginosus subsp. whileyi MAS624]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGATCCAAGTGTAAAAATAACTAAGATTAGCAAAGAACAATTTACTAAAGAATGGACAGGTGTTG
CTATCTTTCTCGCACCAAAACCTAGCTATAAACCTCATAAGGATAAGAAAAATGGACTTGCTAGCTTTTTACCACTCATC
TTTAAACAGCGTTCTTTGATTTTTTATATTGTCTTAGCTAGTTTGCTCGTGACCCTCATCAACATTGTTGGCTCCTATTA
TCTGCAAAGCGTTTTGGACGAATACATCCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATTGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCCAACTCTATTATTGATGCTCTAGCGTCAACAATTCTATCCCTCCTTCTTGATTTGTCCATTTTGATAA
TTGTCGGCAGTGTTCTTTTACTGCAAAATGCCAATCTCTTTCTACTCACTTTGCTTGCAATTCCTATCTACGCTCTCATT
ATTTTTGCTTTTATGAAGCCTTTTGAAAAAATGAACAACGATGTTATGCAAAGCAATGCTATGGTGAATTCTGCTATTAT
CGAAGATATCAATGGAATTGAAACCATTAAATCTTTAACTAGCGAAGAAAGTCGTTACCAAAAGATTGATAGCGAGTTTG
TTGATTATCTGGATAAAACTTTCAAATTAAGTAAATATTCCATTGTGCAGACCGCTCTCAAACAAGGAGCACAATTTGTT
TTGAATGTGGTTATTCTCTGGGTTGGAGCGTCCTTAGTCATGTCTCAAAAGATTTCAATTGGTCAACTGATTACTTTCAA
TGCTCTCCTTTCATACTTTACTAGTCCGCTTGAAAGTATCATCAATCTTCAAACCAAACTGCAATCAGCTAAAGTTGCCA
ATCATCGACTGAATGAAATTTATCTGGTAGAATCTGAATTCAAAACCAAACAAGTCCTTACGGAGAAAAATTTCTTAGCT
GGTGATATTACTTTTCATAACGTCTCCTATAAATATGGCTTTGGACGAGATACTTTATCAGATATTAGTTTAACTATCAA
GAAGGGAGATAAAATCAGTCTTTTCGGTATTAGCGGTTCGGGAAAAACAACACTTGCTAAGATGATTGTTCATTTTTATG
AGCCTTATCAAGGACAAATTCGCCTCAATGGAAATGACCTCAAGACAATTGATAAGAAAGTTCTTCGGCAATATATCAAC
TACTTACCTCAGCAAGCTTACATATTTAGTGGTTCCATTCTAGACAACCTCACATTAGGAGCCGATCAAACAGTTTCTCA
ATCAGATATTCTTCGTGCCTGTGAAATTGCAGAAATTCGTTCAGATATCGAACAAATGCCCATGGGATACCAGACAGAAT
TGTCTGACGGAGCTGGATTATCTGGTGGGCAAAAACAGCGAATCGCACTTGCACGCGCTCTCCTGACGAAATCTCCCATT
CTCATTTTAGATGAAGCAACGAGTGGATTAGATGTTCTAACAGAGAAAAAAGTCATTGATAATCTCATGAAATTACCCGA
CAAAACCATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGTACAAATCAGATTATCGTCCTTGACCAAGGAAAAG
TGATTGAAACGGGTTCTCATACTGAATTGATAGAAAGAAAAGGTTTTTATTATCATCTATTTAATAAATAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(167-437)

ABC transporter (ABC_tran)

(499-648)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.791

99.022

0.711
  comA Streptococcus mitis NCTC 12261

66.339

99.581

0.661
  comA Streptococcus mitis SK321

65.919

99.581

0.656
  comA Streptococcus gordonii str. Challis substr. CH1

65.778

99.581

0.655
  comA Streptococcus pneumoniae D39

65.498

99.581

0.652
  comA Streptococcus pneumoniae R6

65.498

99.581

0.652
  comA Streptococcus pneumoniae Rx1

65.498

99.581

0.652
  comA Streptococcus pneumoniae TIGR4

65.077

99.581

0.648

Multiple sequence alignment