Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD/cglD   Type   Machinery gene
Locus tag   J5M87_RS00625 Genome accession   NZ_CP072115
Coordinates   98485..98847 (+) Length   120 a.a.
NCBI ID   WP_244315564.1    Uniprot ID   -
Organism   Streptococcus zhangguiae strain zg-86     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 97172..121543 98485..98847 within 0


Gene organization within MGE regions


Location: 97172..121543
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5M87_RS00620 (J5M87_00620) comGC/cglC 98145..98459 (+) 315 WP_154607862.1 competence type IV pilus major pilin ComGC Machinery gene
  J5M87_RS00625 (J5M87_00625) comGD/cglD 98485..98847 (+) 363 WP_244315564.1 competence type IV pilus minor pilin ComGD Machinery gene
  J5M87_RS00630 (J5M87_00630) comGE 98819..99112 (+) 294 WP_160463141.1 competence type IV pilus minor pilin ComGE -
  J5M87_RS00635 (J5M87_00635) comYF 99096..99533 (+) 438 WP_154607860.1 competence type IV pilus minor pilin ComGF Machinery gene
  J5M87_RS00640 (J5M87_00640) comGG 99544..99969 (+) 426 WP_154607859.1 competence type IV pilus minor pilin ComGG -
  J5M87_RS00645 (J5M87_00645) - 100330..100782 (-) 453 WP_154607858.1 type II toxin-antitoxin system HicB family antitoxin -
  J5M87_RS00650 (J5M87_00650) - 100820..100999 (-) 180 WP_068993248.1 type II toxin-antitoxin system HicA family toxin -
  J5M87_RS00655 (J5M87_00655) - 101183..101590 (-) 408 WP_154607857.1 ArpU family transcriptional regulator -
  J5M87_RS00660 (J5M87_00660) - 102017..102502 (-) 486 WP_154607856.1 hypothetical protein -
  J5M87_RS09770 - 102595..103116 (-) 522 WP_230082343.1 hypothetical protein -
  J5M87_RS00670 (J5M87_00670) - 103129..103377 (-) 249 WP_154607855.1 hypothetical protein -
  J5M87_RS00675 (J5M87_00675) - 103480..104277 (-) 798 WP_154607854.1 DnaD domain-containing protein -
  J5M87_RS00680 (J5M87_00680) - 104431..104712 (-) 282 WP_154607853.1 hypothetical protein -
  J5M87_RS00685 (J5M87_00685) - 104714..105049 (-) 336 WP_154607852.1 DNA-binding protein -
  J5M87_RS00690 (J5M87_00690) - 105059..105253 (-) 195 WP_154607851.1 hypothetical protein -
  J5M87_RS00695 (J5M87_00695) - 105247..105402 (-) 156 WP_154607850.1 hypothetical protein -
  J5M87_RS00700 (J5M87_00700) - 105399..105722 (-) 324 WP_154607849.1 hypothetical protein -
  J5M87_RS00705 (J5M87_00705) - 105942..106571 (-) 630 WP_154607848.1 Rha family transcriptional regulator -
  J5M87_RS09775 - 106589..106717 (-) 129 WP_348271964.1 helix-turn-helix transcriptional regulator -
  J5M87_RS00715 (J5M87_00715) - 106955..107614 (+) 660 WP_154607847.1 helix-turn-helix transcriptional regulator -
  J5M87_RS00720 (J5M87_00720) dinD 107864..108718 (+) 855 WP_154607846.1 DNA damage-inducible protein D -
  J5M87_RS00725 (J5M87_00725) - 108895..110043 (+) 1149 WP_154607845.1 site-specific integrase -
  J5M87_RS00730 (J5M87_00730) comYH 110143..111096 (+) 954 WP_154607844.1 class I SAM-dependent methyltransferase Machinery gene
  J5M87_RS00735 (J5M87_00735) - 111146..112336 (+) 1191 WP_154607843.1 acetate kinase -
  J5M87_RS00740 (J5M87_00740) - 112612..113472 (+) 861 WP_154607842.1 pyridoxamine kinase -
  J5M87_RS00745 (J5M87_00745) - 113469..113996 (+) 528 WP_154607841.1 ECF transporter S component -
  J5M87_RS00750 (J5M87_00750) - 114226..114780 (+) 555 WP_154607840.1 folate family ECF transporter S component -
  J5M87_RS00755 (J5M87_00755) - 114841..116097 (+) 1257 WP_154607839.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  J5M87_RS00760 (J5M87_00760) pepA 116632..117705 (-) 1074 WP_154607838.1 glutamyl aminopeptidase -
  J5M87_RS00765 (J5M87_00765) - 117757..118041 (+) 285 WP_154607837.1 DUF4651 domain-containing protein -
  J5M87_RS00770 (J5M87_00770) - 118038..118358 (+) 321 WP_154607836.1 thioredoxin family protein -
  J5M87_RS00775 (J5M87_00775) ytpR 118362..118994 (+) 633 WP_154607835.1 YtpR family tRNA-binding protein -
  J5M87_RS00780 (J5M87_00780) ssbB 119059..119454 (+) 396 WP_154607834.1 single-stranded DNA-binding protein Machinery gene
  J5M87_RS00785 (J5M87_00785) groES 119620..119904 (+) 285 WP_154607833.1 co-chaperone GroES -
  J5M87_RS00790 (J5M87_00790) groL 119921..121543 (+) 1623 WP_154607832.1 chaperonin GroEL -

Sequence

Protein


Download         Length: 120 a.a.        Molecular weight: 13678.64 Da        Isoelectric Point: 7.3146

>NTDB_id=550515 J5M87_RS00625 WP_244315564.1 98485..98847(+) (comGD/cglD) [Streptococcus zhangguiae strain zg-86]
MVLFVVSFLTILLSSSVHQIVDATKEQLFFLEFEHLYKSSQKLSVVSQQAVTLELTTHQISNGYETVLVPSSIELDKERR
ILFDRNGGNSSLEKIEFSVGNKTIRYQLYLGSGNYKKTEK

Nucleotide


Download         Length: 363 bp        

>NTDB_id=550515 J5M87_RS00625 WP_244315564.1 98485..98847(+) (comGD/cglD) [Streptococcus zhangguiae strain zg-86]
GTGGTGTTATTTGTTGTCAGTTTTCTAACGATTCTCTTATCCAGTTCGGTTCATCAGATAGTTGATGCTACAAAAGAACA
GCTATTTTTTCTGGAATTTGAACATCTCTACAAATCAAGTCAGAAGTTGTCAGTAGTTTCACAACAAGCTGTTACACTTG
AACTAACAACACATCAGATTTCGAACGGTTATGAGACTGTGTTAGTGCCCTCCTCGATTGAGCTTGACAAAGAACGGCGT
ATCTTATTTGATCGGAATGGAGGAAATTCATCGTTAGAGAAAATTGAATTTTCAGTAGGGAATAAGACAATCAGATATCA
ATTATATTTAGGGAGTGGAAATTATAAAAAAACAGAAAAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD/cglD Streptococcus mitis SK321

50.427

97.5

0.492
  comGD/cglD Streptococcus pneumoniae Rx1

49.573

97.5

0.483
  comGD/cglD Streptococcus pneumoniae D39

49.573

97.5

0.483
  comGD/cglD Streptococcus pneumoniae R6

49.573

97.5

0.483
  comGD/cglD Streptococcus mitis NCTC 12261

49.573

97.5

0.483
  comGD/cglD Streptococcus pneumoniae TIGR4

48.718

97.5

0.475
  comYD Streptococcus mutans UA159

47.5

100

0.475
  comYD Streptococcus mutans UA140

47.5

100

0.475
  comYD Streptococcus gordonii str. Challis substr. CH1

45.763

98.333

0.45