Detailed information NTG0550480

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: J5Z97_RS04860
• Genome accession: NZ_CP072112
• Coordinates: 949381..950217 (+)
• Length: 278 a.a.
• NCBI ID: WP_023611073.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M08500
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 944381..955217

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J5Z97_RS04830 (J5Z97_04830)	-	944932..945303 (+)	372	WP_208769233.1	hypothetical protein	-
J5Z97_RS04835 (J5Z97_04835)	-	945353..946264 (-)	912	WP_023611071.1	diacylglycerol kinase family protein	-
J5Z97_RS04840 (J5Z97_04840)	-	946381..947031 (-)	651	WP_002984629.1	hemolysin III family protein	-
J5Z97_RS04845 (J5Z97_04845)	-	947028..947468 (-)	441	WP_023611062.1	DUF1836 domain-containing protein	-
J5Z97_RS04850 (J5Z97_04850)	ylqF	947687..948535 (+)	849	WP_023611048.1	ribosome biogenesis GTPase YlqF	-
J5Z97_RS04855 (J5Z97_04855)	-	948525..949316 (+)	792	WP_023611055.1	ribonuclease HII	-
J5Z97_RS04860 (J5Z97_04860)	dprA	949381..950217 (+)	837	WP_023611073.1	DNA-processing protein DprA	Machinery gene
J5Z97_RS04865 (J5Z97_04865)	topA	950325..952454 (+)	2130	WP_023611066.1	type I DNA topoisomerase	-
J5Z97_RS04870 (J5Z97_04870)	-	952529..953270 (-)	742	Protein_911	LysR family transcriptional regulator	-
J5Z97_RS04875 (J5Z97_04875)	-	953310..953876 (+)	567	Protein_912	PTS sugar transporter subunit IIC	-
J5Z97_RS04880 (J5Z97_04880)	-	953891..954883 (+)	993	WP_063662247.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31018.97 Da
• Isoelectric Point: 8.8230

>NTDB_id=550480 J5Z97_RS04860 WP_023611073.1 949381..950217(+) (dprA) [Streptococcus pyogenes strain M08500]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEESR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=550480 J5Z97_RS04860 WP_023611073.1 949381..950217(+) (dprA) [Streptococcus pyogenes strain M08500]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAAGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367