Detailed information NTG0548650

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: JN057_RS10025
• Genome accession: NZ_CP071871
• Coordinates: 1927343..1927804 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250531.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain BVJ1JL
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1922343..1932804

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN057_RS09995 (JN057_02049)	-	1922647..1923471 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
JN057_RS10000 (JN057_02050)	rnpA	1923446..1923817 (-)	372	WP_000739246.1	ribonuclease P protein component	-
JN057_RS11610	-	1923834..1923965 (-)	132	WP_000768904.1	hypothetical protein	-
JN057_RS10005 (JN057_02051)	-	1923966..1925156 (-)	1191	WP_000167766.1	acetate kinase	-
JN057_RS10010 (JN057_02052)	comYH	1925207..1926160 (-)	954	WP_000345116.1	class I SAM-dependent methyltransferase	Machinery gene
JN057_RS10015	-	1926221..1926815 (-)	595	Protein_1964	class I SAM-dependent methyltransferase	-
JN057_RS10020 (JN057_02054)	comGG/cglG	1926952..1927365 (-)	414	WP_061370822.1	competence type IV pilus minor pilin ComGG	Machinery gene
JN057_RS10025 (JN057_02055)	comGF/cglF	1927343..1927804 (-)	462	WP_000250531.1	competence type IV pilus minor pilin ComGF	Machinery gene
JN057_RS10030 (JN057_02056)	comGE/cglE	1927767..1928069 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
JN057_RS10035 (JN057_02057)	comGD/cglD	1928032..1928436 (-)	405	WP_000588020.1	competence type IV pilus minor pilin ComGD	Machinery gene
JN057_RS10040 (JN057_02058)	comGC/cglC	1928429..1928755 (-)	327	WP_000738633.1	comG operon protein ComGC	Machinery gene
JN057_RS10045 (JN057_02059)	comGB/cglB	1928757..1929773 (-)	1017	WP_001844679.1	competence type IV pilus assembly protein ComGB	Machinery gene
JN057_RS10050 (JN057_02060)	comGA/cglA/cilD	1929721..1930662 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
JN057_RS10055 (JN057_02061)	-	1930738..1931103 (-)	366	WP_000286415.1	DUF1033 family protein	-
JN057_RS10060 (JN057_02062)	-	1931254..1932312 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17849.37 Da
• Isoelectric Point: 6.4832

>NTDB_id=548650 JN057_RS10025 WP_000250531.1 1927343..1927804(-) (comGF/cglF) [Streptococcus pneumoniae strain BVJ1JL]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=548650 JN057_RS10025 WP_000250531.1 1927343..1927804(-) (comGF/cglF) [Streptococcus pneumoniae strain BVJ1JL]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGTAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae D39	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae R6	95.425	100	0.954
comGF/cglF	Streptococcus pneumoniae TIGR4	95.425	100	0.954
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915