Detailed information NTG0548644

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: JN057_RS09565
• Genome accession: NZ_CP071871
• Coordinates: 1847293..1848330 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: A0AAQ2ZXI6
• Organism: Streptococcus pneumoniae strain BVJ1JL
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1842293..1853330

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN057_RS09540 (JN057_01954)	-	1843032..1844363 (-)	1332	WP_000390039.1	hemolysin family protein	-
JN057_RS09545 (JN057_01955)	endA	1844654..1845478 (-)	825	WP_001036790.1	DNA-entry nuclease EndA	Machinery gene
JN057_RS09550 (JN057_01956)	-	1845517..1845705 (-)	189	WP_001818955.1	DNA-directed RNA polymerase subunit beta	-
JN057_RS09555 (JN057_01957)	murA	1845698..1846981 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
JN057_RS09560 (JN057_01958)	-	1847005..1847235 (-)	231	WP_000250392.1	DUF1146 family protein	-
JN057_RS09565 (JN057_01959)	sepM	1847293..1848330 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
JN057_RS09570 (JN057_01960)	coaD	1848314..1848802 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
JN057_RS09575 (JN057_01961)	rsmD	1848792..1849331 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
JN057_RS09580 (JN057_01962)	asnA	1849396..1850388 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
JN057_RS09585 (JN057_01963)	-	1850500..1851183 (-)	684	WP_208093483.1	Bax inhibitor-1/YccA family protein	-
JN057_RS09590 (JN057_01964)	-	1851239..1851979 (-)	741	WP_000152701.1	TrmH family RNA methyltransferase	-
JN057_RS09595 (JN057_01965)	-	1852013..1852291 (+)	279	WP_001174613.1	acylphosphatase	-
JN057_RS09600 (JN057_01966)	yidC	1852369..1853295 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=548644 JN057_RS09565 WP_000727276.1 1847293..1848330(-) (sepM) [Streptococcus pneumoniae strain BVJ1JL]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=548644 JN057_RS09565 WP_000727276.1 1847293..1848330(-) (sepM) [Streptococcus pneumoniae strain BVJ1JL]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588