Detailed information NTG0548645

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JN057_RS09725
• Genome accession: NZ_CP071871
• Coordinates: 1876691..1877701 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain BVJ1JL
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1871691..1882701

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JN057_RS09700 (JN057_01989)	-	1872901..1873194 (-)	294	WP_000977367.1	hypothetical protein	-
JN057_RS09705 (JN057_01990)	-	1873356..1873808 (+)	453	WP_000079154.1	universal stress protein	-
JN057_RS09710 (JN057_01991)	-	1873843..1875231 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
JN057_RS09715 (JN057_01992)	-	1875297..1876259 (+)	963	WP_001124777.1	asparaginase	-
JN057_RS09720 (JN057_01993)	-	1876256..1876627 (-)	372	WP_001092050.1	hypothetical protein	-
JN057_RS09725 (JN057_01994)	ccpA	1876691..1877701 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
JN057_RS09730 (JN057_01995)	-	1878126..1878725 (-)	600	WP_000866726.1	response regulator transcription factor	-
JN057_RS09735 (JN057_01996)	-	1878727..1879824 (-)	1098	WP_061370749.1	sensor histidine kinase	-
JN057_RS09740 (JN057_01997)	-	1879824..1880561 (-)	738	WP_000832838.1	ABC transporter permease	-
JN057_RS09745 (JN057_01998)	-	1880563..1881447 (-)	885	WP_061370750.1	ABC transporter ATP-binding protein	-
JN057_RS09750 (JN057_01999)	-	1881434..1881628 (-)	195	WP_000820179.1	hypothetical protein	-
JN057_RS09755 (JN057_02000)	-	1881625..1881831 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=548645 JN057_RS09725 WP_000990607.1 1876691..1877701(-) (ccpA) [Streptococcus pneumoniae strain BVJ1JL]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=548645 JN057_RS09725 WP_000990607.1 1876691..1877701(-) (ccpA) [Streptococcus pneumoniae strain BVJ1JL]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGCTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAAGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCTATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568