Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   SYN6312_RS00135 Genome accession   NC_019680
Coordinates   32551..32922 (-) Length   123 a.a.
NCBI ID   WP_015122829.1    Uniprot ID   K9RMV9
Organism   Synechococcus sp. PCC 6312     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 27551..37922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SYN6312_RS20850 (Syn6312_0025) - 28109..31861 (-) 3753 WP_015122827.1 HAMP domain-containing methyl-accepting chemotaxis protein -
  SYN6312_RS00130 (Syn6312_0026) - 32021..32551 (-) 531 WP_015122828.1 chemotaxis protein CheW -
  SYN6312_RS00135 (Syn6312_0027) pilH 32551..32922 (-) 372 WP_015122829.1 response regulator transcription factor Machinery gene
  SYN6312_RS00140 (Syn6312_0028) cysH 33326..34042 (-) 717 WP_015122830.1 phosphoadenosine phosphosulfate reductase -
  SYN6312_RS00145 (Syn6312_0029) - 34123..34413 (-) 291 WP_015122831.1 YggT family protein -
  SYN6312_RS00150 (Syn6312_0030) - 34501..34788 (-) 288 WP_015122832.1 hypothetical protein -
  SYN6312_RS00155 (Syn6312_0031) upp 34832..35482 (-) 651 WP_015122833.1 uracil phosphoribosyltransferase -
  SYN6312_RS00160 (Syn6312_0032) - 35958..36131 (+) 174 WP_015122834.1 chlorophyll a/b-binding protein -
  SYN6312_RS00165 (Syn6312_0033) - 36230..37756 (-) 1527 WP_015122835.1 hypothetical protein -

Sequence

Protein


Download         Length: 123 a.a.        Molecular weight: 13451.61 Da        Isoelectric Point: 4.6952

>NTDB_id=54684 SYN6312_RS00135 WP_015122829.1 32551..32922(-) (pilH) [Synechococcus sp. PCC 6312]
MSNVLVVEDSAPQREMISELLAKSGMTVALATDGVEALEQVKALQPDIVVLDIVMPRKNGYEVCREIKSDPSTQNVPVII
CSSKGEDFDKYWGMKQGADAYIVKPFQPKELIGTIKQLLRGAG

Nucleotide


Download         Length: 372 bp        

>NTDB_id=54684 SYN6312_RS00135 WP_015122829.1 32551..32922(-) (pilH) [Synechococcus sp. PCC 6312]
ATGAGTAACGTGTTAGTTGTTGAAGACAGTGCGCCCCAACGGGAAATGATCAGTGAGCTTCTGGCTAAGTCGGGGATGAC
CGTTGCGTTGGCGACTGACGGGGTAGAAGCACTGGAACAGGTCAAGGCTCTGCAACCCGATATTGTTGTTCTCGATATTG
TCATGCCTCGTAAAAATGGCTATGAGGTCTGTCGGGAAATTAAGTCAGATCCGAGTACCCAGAACGTTCCAGTCATTATC
TGTAGCTCCAAAGGCGAGGACTTTGATAAGTATTGGGGCATGAAACAGGGAGCAGATGCCTATATTGTCAAGCCTTTTCA
GCCGAAAGAATTAATTGGCACAATCAAGCAACTATTGAGGGGAGCCGGGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K9RMV9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Synechocystis sp. PCC 6803

71.074

98.374

0.699
  micA Streptococcus pneumoniae Cp1015

41.667

97.561

0.407
  pilG Acinetobacter baumannii strain A118

42.982

92.683

0.398
  vicR Streptococcus mutans UA159

38.333

97.561

0.374
  pilL-C Synechocystis sp. PCC 6803

38.333

97.561

0.374
  scnR Streptococcus mutans UA159

37.5

97.561

0.366

Multiple sequence alignment