Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H020_RS0105775 Genome accession   NZ_AKVY01000001
Coordinates   1106293..1106757 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae TIGR4     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1101293..1111757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H020_RS0105755 - 1102244..1103212 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  H020_RS0105760 pdrM 1103366..1104727 (-) 1362 WP_000278524.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  H020_RS0105765 - 1104738..1104998 (-) 261 WP_001105925.1 hypothetical protein -
  H020_RS0105770 - 1105012..1106280 (-) 1269 WP_000924508.1 dihydroorotase -
  H020_RS0105775 mutX 1106293..1106757 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  H020_RS0105780 - 1106767..1107420 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  H020_RS0105785 - 1107558..1108160 (-) 603 WP_001812270.1 hypothetical protein -
  H020_RS0105790 - 1108218..1108931 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  H020_RS0105795 dhaM 1109391..1109765 (-) 375 WP_000443795.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  H020_RS14670 - 1109765..1109839 (-) 75 Protein_1105 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=54684 H020_RS0105775 WP_001135768.1 1106293..1106757(-) (mutX) [Streptococcus pneumoniae TIGR4]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=54684 H020_RS0105775 WP_001135768.1 1106293..1106757(-) (mutX) [Streptococcus pneumoniae TIGR4]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment