Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   J0J35_RS07965 Genome accession   NZ_CP071301
Coordinates   1615567..1616784 (+) Length   405 a.a.
NCBI ID   WP_019291567.1    Uniprot ID   A0AAJ2IZW6
Organism   Lactococcus sp. LG606     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610567..1621784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0J35_RS07935 (J0J35_07935) eeP 1610578..1611825 (-) 1248 WP_086583290.1 RIP metalloprotease RseP Regulator
  J0J35_RS07940 (J0J35_07940) - 1612002..1612796 (-) 795 WP_019291563.1 phosphatidate cytidylyltransferase -
  J0J35_RS07945 (J0J35_07945) - 1612793..1613530 (-) 738 WP_019292981.1 isoprenyl transferase -
  J0J35_RS07950 (J0J35_07950) yajC 1613730..1614065 (-) 336 WP_019292982.1 preprotein translocase subunit YajC -
  J0J35_RS07955 (J0J35_07955) - 1614140..1614787 (-) 648 WP_046401302.1 DNA alkylation repair protein -
  J0J35_RS07960 (J0J35_07960) rlmH 1614784..1615263 (-) 480 WP_019291566.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  J0J35_RS07965 (J0J35_07965) htrA 1615567..1616784 (+) 1218 WP_019291567.1 S1C family serine protease Regulator
  J0J35_RS07970 (J0J35_07970) - 1616881..1617879 (+) 999 WP_206916548.1 glycosyltransferase family 4 protein -
  J0J35_RS07975 (J0J35_07975) - 1617892..1619226 (+) 1335 WP_019291569.1 glycosyltransferase family 4 protein -
  J0J35_RS07980 (J0J35_07980) - 1619277..1619501 (+) 225 WP_003133519.1 DUF1797 family protein -
  J0J35_RS07985 (J0J35_07985) - 1619531..1620580 (-) 1050 WP_206916550.1 BMP family protein -
  J0J35_RS07990 (J0J35_07990) - 1620739..1621488 (-) 750 WP_206916552.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 41831.68 Da        Isoelectric Point: 4.8866

>NTDB_id=544807 J0J35_RS07965 WP_019291567.1 1615567..1616784(+) (htrA) [Lactococcus sp. LG606]
MAKKNIASLLITGVAGGAIALGGSAIYQNMTNTPSSNNTSDNSVSTVNVQVNTDTTKAIKKISNTVVSVLNYQKSSSSND
FEKIFGGGDTSSNESNTPQLAGEGSGVIYKKDGNTAYIVTNYHVIEGASSLEVLMAGGQKVTAEVVGSDAYSDLAVLKID
AKYVKETATFGNSDKLTVGEPAIAVGSPLGSEYANSATEGIVSSLNRNVTLQNSQGQTINVNAIQTDAAINPGNSGGALI
NIQGQVIGITSSKITSTPSGTSSSGVSVEGMGFAIPANDVVNIINKLEKDGKVIRPALGVQMVNLSSLSQNMLASLNLPE
NVTNGVAIAEVQSGMPAAKAGLKQGDVIVKINDDEITSSVNLQSTLYKSSIGDTIKVTYYRDGKQATANIKLDKTSSDIN
FDKQN

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=544807 J0J35_RS07965 WP_019291567.1 1615567..1616784(+) (htrA) [Lactococcus sp. LG606]
ATGGCAAAAAAAAATATCGCCTCATTACTTATTACAGGCGTAGCCGGAGGTGCTATCGCTCTCGGAGGTAGTGCTATCTA
CCAAAATATGACCAACACGCCGTCATCTAACAACACTTCGGACAATTCTGTAAGTACAGTTAACGTCCAAGTAAATACAG
ATACTACAAAAGCAATCAAGAAAATTTCGAACACTGTTGTTTCCGTTCTTAATTACCAAAAATCGTCCTCAAGCAACGAT
TTTGAGAAGATTTTCGGCGGAGGCGATACAAGTAGCAATGAGAGTAATACGCCACAGCTGGCTGGAGAGGGTTCTGGTGT
TATTTACAAAAAGGATGGCAATACAGCATATATCGTCACCAACTATCACGTTATTGAAGGTGCTTCTTCCCTAGAAGTTC
TCATGGCTGGTGGTCAAAAGGTTACTGCTGAAGTTGTTGGTTCTGATGCTTATTCTGATTTAGCTGTCCTCAAAATTGAT
GCTAAGTATGTCAAAGAAACAGCAACATTCGGCAACTCTGACAAACTTACTGTTGGTGAGCCCGCTATCGCGGTGGGTTC
TCCCCTTGGAAGTGAGTATGCAAACTCAGCAACAGAAGGAATTGTTTCAAGTCTAAATCGCAATGTTACACTGCAAAACA
GCCAAGGCCAAACAATTAATGTTAACGCTATTCAAACCGATGCAGCTATTAACCCCGGTAACTCTGGTGGTGCACTCATA
AATATTCAAGGACAAGTCATCGGGATTACCTCAAGTAAAATTACCTCAACACCAAGCGGAACAAGCAGCAGTGGTGTCTC
TGTAGAAGGTATGGGATTTGCGATTCCAGCCAATGATGTCGTTAACATTATCAATAAGTTGGAAAAAGATGGCAAAGTTA
TTCGACCTGCTCTCGGTGTACAAATGGTCAACTTGTCAAGTCTTTCCCAAAATATGTTAGCTTCACTTAACCTTCCTGAA
AACGTGACTAACGGTGTTGCTATCGCTGAAGTTCAATCAGGAATGCCTGCTGCCAAAGCTGGACTCAAGCAAGGCGACGT
TATTGTCAAAATCAATGATGACGAAATCACTTCAAGCGTGAACCTTCAAAGTACACTTTATAAGTCTTCAATTGGTGATA
CGATTAAGGTAACTTATTATCGTGACGGAAAACAGGCTACTGCGAATATCAAATTGGATAAAACAAGTAGTGATATCAAC
TTTGACAAACAAAATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(104-249)

Peptidase family M50 (Peptidase_M50)

(288-396)

PDZ domain (PDZ_2)

(296-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

54.476

96.543

0.526
  htrA Streptococcus mutans UA159

56.349

93.333

0.526
  htrA Streptococcus mitis NCTC 12261

52.882

98.519

0.521
  htrA Streptococcus pneumoniae TIGR4

52.632

98.519

0.519
  htrA Streptococcus pneumoniae D39

52.632

98.519

0.519
  htrA Streptococcus pneumoniae Rx1

52.632

98.519

0.519
  htrA Streptococcus pneumoniae R6

52.632

98.519

0.519