Detailed information NTG0542021

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: JYQ80_RS04440
• Genome accession: NZ_CP070994
• Coordinates: 891397..892233 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M11318
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 886397..897233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JYQ80_RS04410 (JYQ80_04410)	-	886951..887319 (+)	369	WP_010922310.1	hypothetical protein	-
JYQ80_RS04415 (JYQ80_04415)	-	887369..888280 (-)	912	WP_010922311.1	diacylglycerol/lipid kinase family protein	-
JYQ80_RS04420 (JYQ80_04420)	trhA	888397..889047 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
JYQ80_RS04425 (JYQ80_04425)	-	889044..889484 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
JYQ80_RS04430 (JYQ80_04430)	ylqF	889703..890551 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
JYQ80_RS04435 (JYQ80_04435)	-	890541..891332 (+)	792	WP_011285534.1	ribonuclease HII	-
JYQ80_RS04440 (JYQ80_04440)	dprA	891397..892233 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
JYQ80_RS04445 (JYQ80_04445)	topA	892340..894469 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
JYQ80_RS04450 (JYQ80_04450)	-	894544..895426 (-)	883	Protein_845	LysR family transcriptional regulator	-
JYQ80_RS04455 (JYQ80_04455)	-	895439..895984 (+)	546	Protein_846	PTS sugar transporter subunit IIC	-
JYQ80_RS04460 (JYQ80_04460)	-	895999..896991 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=542021 JYQ80_RS04440 WP_010922314.1 891397..892233(+) (dprA) [Streptococcus pyogenes strain M11318]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=542021 JYQ80_RS04440 WP_010922314.1 891397..892233(+) (dprA) [Streptococcus pyogenes strain M11318]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367