Detailed information NTG0053963

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: GGS_RS05090
• Genome accession: NC_018712
• Coordinates: 1023801..1024637 (-)
• Length: 278 a.a.
• NCBI ID: WP_015017018.1
• Uniprot ID: A0AB38Y445
• Organism: Streptococcus dysgalactiae subsp. equisimilis RE378
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1018801..1029637

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GGS_RS05075 (GGS_0968)	-	1019610..1020473 (+)	864	WP_003059102.1	IS982-like element ISSpy2 family transposase	-
GGS_RS10890	-	1020578..1021455 (+)	878	Protein_968	LysR family transcriptional regulator	-
GGS_RS05085 (GGS_0970)	topA	1021531..1023693 (-)	2163	WP_015017017.1	type I DNA topoisomerase	-
GGS_RS05090 (GGS_0971)	dprA	1023801..1024637 (-)	837	WP_015017018.1	DNA-processing protein DprA	Machinery gene
GGS_RS05095 (GGS_0972)	-	1024702..1025493 (-)	792	WP_015017019.1	ribonuclease HII	-
GGS_RS05100 (GGS_0973)	ylqF	1025483..1026331 (-)	849	WP_042357910.1	ribosome biogenesis GTPase YlqF	-
GGS_RS05105	-	1027054..1027284 (-)	231	WP_003062326.1	hypothetical protein	-
GGS_RS05110 (GGS_0974)	-	1027503..1028390 (-)	888	WP_015017021.1	Rgg/GadR/MutR family transcriptional regulator	-
GGS_RS05115 (GGS_0975)	-	1028729..1029169 (+)	441	WP_003060620.1	DUF1836 domain-containing protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31000.06 Da
• Isoelectric Point: 9.2514

>NTDB_id=53963 GGS_RS05090 WP_015017018.1 1023801..1024637(-) (dprA) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQIFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=53963 GGS_RS05090 WP_015017018.1 1023801..1024637(-) (dprA) [Streptococcus dysgalactiae subsp. equisimilis RE378]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAATTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367