Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   GGS_RS02860 Genome accession   NC_018712
Coordinates   552630..553340 (+) Length   236 a.a.
NCBI ID   WP_012766682.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis RE378     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 547630..558340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GGS_RS02835 (GGS_0538) - 548309..549304 (+) 996 WP_042357864.1 DUF3114 domain-containing protein -
  GGS_RS02840 (GGS_0539) - 549400..550047 (-) 648 WP_003057245.1 amino acid ABC transporter permease -
  GGS_RS02845 (GGS_0540) - 550062..550763 (-) 702 WP_015016780.1 amino acid ABC transporter permease -
  GGS_RS02850 (GGS_0541) - 550777..551577 (-) 801 WP_003057243.1 transporter substrate-binding domain-containing protein -
  GGS_RS02855 (GGS_0542) - 551577..552371 (-) 795 WP_003057217.1 amino acid ABC transporter ATP-binding protein -
  GGS_RS02860 (GGS_0543) vicR 552630..553340 (+) 711 WP_012766682.1 response regulator YycF Regulator
  GGS_RS02865 (GGS_0544) vicK 553333..554686 (+) 1354 Protein_527 cell wall metabolism sensor histidine kinase VicK -
  GGS_RS02870 (GGS_0545) vicX 554690..555499 (+) 810 WP_003059746.1 MBL fold metallo-hydrolase Regulator
  GGS_RS02875 (GGS_0546) rnc 556257..556949 (+) 693 WP_003057240.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.95 Da        Isoelectric Point: 5.0023

>NTDB_id=53955 GGS_RS02860 WP_012766682.1 552630..553340(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=53955 GGS_RS02860 WP_012766682.1 552630..553340(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis RE378]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment