NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	LIO33_RS04650	Genome accession	NZ_CP085088
Coordinates	941814..942485 (-)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain Ssuis_MA1
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 936814..947485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LIO33_RS04630	rpsT	937613..937861 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
LIO33_RS04635	tnpA	938003..938467 (-)	465	WP_012775157.1	IS200/IS605-like element ISSsu4 family transposase	-
LIO33_RS04640	-	938882..940111 (-)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
LIO33_RS04645	ciaH	940442..941821 (-)	1380	WP_012027074.1	cell wall metabolism sensor histidine kinase WalK	Regulator
LIO33_RS04650	ciaR	941814..942485 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
LIO33_RS04655	-	942679..943059 (-)	381	WP_012027076.1	hypothetical protein	-
LIO33_RS04660	-	943444..944646 (+)	1203	WP_012775158.1	IS110 family transposase	-
LIO33_RS04665	phoU	944848..945504 (-)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
LIO33_RS04670	pstB	945533..946291 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
LIO33_RS04675	pstB	946303..947106 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=537408 LIO33_RS04650 WP_009909965.1 941814..942485(-) (ciaR) [Streptococcus suis strain Ssuis_MA1]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=537408 LIO33_RS04650 WP_009909965.1 941814..942485(-) (ciaR) [Streptococcus suis strain Ssuis_MA1]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT

TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0537408