NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	LIO31_RS05750	Genome accession	NZ_CP085086
Coordinates	1139698..1140369 (-)	Length	223 a.a.
NCBI ID	WP_024394126.1	Uniprot ID	-
Organism	Streptococcus suis strain Ssuis_MA6
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1134698..1145369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LIO31_RS05730	coaA	1135284..1136204 (+)	921	WP_002935283.1	type I pantothenate kinase	-
LIO31_RS05735	rpsT	1136263..1136511 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
LIO31_RS05740	-	1136773..1138002 (-)	1230	WP_023369936.1	transglutaminase domain-containing protein	-
LIO31_RS05745	ciaH	1138326..1139705 (-)	1380	WP_024383407.1	cell wall metabolism sensor histidine kinase WalK	Regulator
LIO31_RS05750	ciaR	1139698..1140369 (-)	672	WP_024394126.1	response regulator transcription factor	Regulator
LIO31_RS05755	-	1140563..1140943 (-)	381	WP_023369940.1	hypothetical protein	-
LIO31_RS05760	-	1141328..1142530 (+)	1203	WP_319022933.1	IS110 family transposase	-
LIO31_RS05765	phoU	1142732..1143388 (-)	657	WP_002937611.1	phosphate signaling complex protein PhoU	-
LIO31_RS05770	pstB	1143417..1144175 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
LIO31_RS05775	pstB	1144187..1144990 (-)	804	WP_074389641.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25306.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=537217 LIO31_RS05750 WP_024394126.1 1139698..1140369(-) (ciaR) [Streptococcus suis strain Ssuis_MA6]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=537217 LIO31_RS05750 WP_024394126.1 1139698..1140369(-) (ciaR) [Streptococcus suis strain Ssuis_MA6]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT

TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGATCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGACCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTCGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.583	100	0.906
ciaR	Streptococcus pneumoniae Rx1	88.789	100	0.888
ciaR	Streptococcus pneumoniae D39	88.789	100	0.888
ciaR	Streptococcus pneumoniae R6	88.789	100	0.888
ciaR	Streptococcus pneumoniae TIGR4	88.789	100	0.888
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.053	100	0.386
vicR	Streptococcus mutans UA159	35.897	100	0.377
micA	Streptococcus pneumoniae Cp1015	34.764	100	0.363

Detailed information NTG0537217