Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   LIO34_RS06135 Genome accession   NZ_CP085085
Coordinates   1217419..1218090 (-) Length   223 a.a.
NCBI ID   WP_009909965.1    Uniprot ID   -
Organism   Streptococcus suis strain Ssuis_MA8     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1212419..1223090
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LIO34_RS06115 coaA 1213005..1213925 (+) 921 WP_002935283.1 type I pantothenate kinase -
  LIO34_RS06120 rpsT 1213984..1214232 (+) 249 WP_012027069.1 30S ribosomal protein S20 -
  LIO34_RS06125 - 1214494..1215723 (-) 1230 WP_002935288.1 transglutaminase domain-containing protein -
  LIO34_RS06130 ciaH 1216047..1217426 (-) 1380 WP_002935290.1 cell wall metabolism sensor histidine kinase WalK Regulator
  LIO34_RS06135 ciaR 1217419..1218090 (-) 672 WP_009909965.1 response regulator transcription factor Regulator
  LIO34_RS06140 - 1218284..1218664 (-) 381 WP_002935294.1 hypothetical protein -
  LIO34_RS06145 - 1219049..1220251 (+) 1203 WP_009909264.1 IS110-like element ISSsu7 family transposase -
  LIO34_RS06150 phoU 1220453..1221109 (-) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  LIO34_RS06155 pstB 1221138..1221896 (-) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  LIO34_RS06160 pstB 1221908..1222711 (-) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 223 a.a.        Molecular weight: 25290.00 Da        Isoelectric Point: 4.2183

>NTDB_id=537124 LIO34_RS06135 WP_009909965.1 1217419..1218090(-) (ciaR) [Streptococcus suis strain Ssuis_MA8]
MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA
KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY
FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide


Download         Length: 672 bp        

>NTDB_id=537124 LIO34_RS06135 WP_009909965.1 1217419..1218090(-) (ciaR) [Streptococcus suis strain Ssuis_MA8]
ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT
TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTGATGT
TGCCTGAAAAAGATGGCTTCCAAGTCTTGAAAGAATTACGTGAAAAAGGTGTTACGACACCTGTTCTGATTACAACAGCC
AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA
ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG
TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGCTAGGAAAAGAATTTGATCTACTAGTTTAT
TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT
TTCAGTAGTAGAAGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACCTTTGGGGAAAATCTTCAAACCCTGC
GTAGTGTCGGATACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

90.135

100

0.901
  ciaR Streptococcus pneumoniae Rx1

88.341

100

0.883
  ciaR Streptococcus pneumoniae D39

88.341

100

0.883
  ciaR Streptococcus pneumoniae R6

88.341

100

0.883
  ciaR Streptococcus pneumoniae TIGR4

88.341

100

0.883
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.39
  vicR Streptococcus mutans UA159

35.47

100

0.372
  covR Streptococcus salivarius strain HSISS4

35.841

100

0.363