Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C270_RS07315 Genome accession   NC_018673
Coordinates   1487991..1489130 (-) Length   379 a.a.
NCBI ID   WP_014974933.1    Uniprot ID   K0DBT5
Organism   Leuconostoc carnosum JB16     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1482991..1494130
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C270_RS07295 (C270_07045) mutY 1483079..1484101 (-) 1023 WP_014974928.1 A/G-specific adenine glycosylase -
  C270_RS09040 (C270_07050) - 1484225..1484368 (+) 144 WP_014974929.1 hypothetical protein -
  C270_RS07300 (C270_07055) - 1484508..1485905 (+) 1398 WP_014974930.1 DHA2 family efflux MFS transporter permease subunit -
  C270_RS07305 (C270_07060) thiD 1485971..1486780 (-) 810 WP_014974931.1 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase -
  C270_RS07310 (C270_07065) rlmH 1486858..1487337 (-) 480 WP_014974932.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  C270_RS07315 (C270_07070) htrA 1487991..1489130 (-) 1140 WP_014974933.1 trypsin-like peptidase domain-containing protein Regulator
  C270_RS07320 (C270_07075) yycI 1489194..1489979 (-) 786 WP_014974934.1 two-component system regulatory protein YycI -
  C270_RS07325 (C270_07080) yycH 1490010..1491314 (-) 1305 WP_014974935.1 two-component system activity regulator YycH -
  C270_RS07330 (C270_07085) walK 1491304..1493175 (-) 1872 WP_014974936.1 cell wall metabolism sensor histidine kinase WalK -
  C270_RS07335 (C270_07090) yycF 1493307..1494014 (-) 708 WP_014974937.1 response regulator YycF -

Sequence

Protein


Download         Length: 379 a.a.        Molecular weight: 39605.04 Da        Isoelectric Point: 9.6237

>NTDB_id=53678 C270_RS07315 WP_014974933.1 1487991..1489130(-) (htrA) [Leuconostoc carnosum JB16]
MKQYSLTKIVLTGIIAGVIGGSALLYGQRGVENLQTSTQKVNTKASETSTIPKNATATTAYDKISDAVVSVLNFSQTGQR
RYEESSEGSGVIYKKAGDSAYIVTNNHVISGASKIQVMMHDGKKVEASLVGKDIMTDLAVLKMDAKNVTATASFGDSNKI
QVGQKVLAIGSPLGSQYASSVTQGIISAKKRLVEASSENGQSYGGSTVIQTDAAINPGNSGGPLINFAGQVIGINSMKLS
SSSSGTSVEGMGFAIPSDQVVNIVNELVKNGKITRPAIGISLVELSEITVDDQKALLKIPETVTGGVVVMGTTDNGPAAK
AGLKKYDVITAIEGKTVAGQADLREELYKHKLGDTISVTYYHQATKHTVNIKLTQKLGS

Nucleotide


Download         Length: 1140 bp        

>NTDB_id=53678 C270_RS07315 WP_014974933.1 1487991..1489130(-) (htrA) [Leuconostoc carnosum JB16]
ATGAAACAATATTCATTAACAAAAATCGTATTAACTGGTATCATCGCTGGTGTTATCGGTGGTAGCGCATTATTATATGG
GCAACGTGGTGTTGAAAATTTGCAAACATCGACACAAAAGGTTAACACAAAGGCTAGTGAAACTAGTACTATCCCCAAAA
ACGCTACAGCCACAACGGCTTATGATAAAATCTCTGATGCTGTTGTTTCAGTATTAAATTTTTCACAAACTGGTCAGAGA
CGCTATGAAGAGTCATCTGAAGGTTCTGGTGTGATTTACAAGAAAGCCGGCGATTCAGCCTATATCGTGACCAATAATCA
CGTGATTAGCGGTGCCTCTAAGATTCAAGTAATGATGCATGATGGTAAAAAGGTTGAAGCATCATTAGTCGGCAAAGATA
TCATGACTGATTTAGCTGTTTTAAAAATGGATGCCAAAAATGTGACGGCAACGGCATCATTTGGTGATTCGAATAAAATT
CAAGTTGGGCAAAAGGTGTTAGCTATCGGTTCCCCCTTGGGTTCACAGTACGCTTCTTCAGTGACTCAAGGTATCATTTC
TGCCAAAAAACGTTTAGTTGAGGCGAGCTCTGAAAACGGGCAAAGTTATGGCGGATCAACAGTTATTCAGACAGATGCTG
CTATTAATCCTGGTAATTCAGGTGGACCACTGATTAATTTTGCAGGTCAAGTCATTGGTATTAACTCAATGAAATTATCC
TCCTCCTCATCTGGTACGAGCGTTGAAGGGATGGGATTTGCAATACCTTCAGATCAGGTGGTTAACATTGTCAATGAACT
GGTGAAGAATGGTAAAATCACAAGGCCGGCTATTGGTATTAGCTTAGTCGAACTTTCCGAAATAACGGTTGATGACCAAA
AAGCTTTACTGAAAATTCCAGAAACTGTAACAGGTGGTGTCGTGGTCATGGGCACGACGGATAATGGGCCGGCAGCTAAA
GCTGGTTTGAAGAAGTACGACGTGATTACTGCTATTGAAGGTAAAACAGTGGCTGGTCAAGCAGACTTGCGTGAGGAGCT
CTACAAGCATAAATTAGGAGACACAATCAGCGTAACCTACTATCACCAAGCAACCAAGCACACAGTCAATATTAAATTAA
CACAGAAATTAGGAAGCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(276-373)

Trypsin-like peptidase domain (Trypsin_2)

(88-234)

Peptidase family M50 (Peptidase_M50)

(201-375)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0DBT5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mitis NCTC 12261

47.044

100

0.483
  htrA Streptococcus mutans UA159

52.059

89.71

0.467
  htrA Streptococcus gordonii str. Challis substr. CH1

46.438

100

0.464
  htrA Streptococcus pneumoniae TIGR4

50.729

90.501

0.459
  htrA Streptococcus pneumoniae D39

50.729

90.501

0.459
  htrA Streptococcus pneumoniae Rx1

50.729

90.501

0.459
  htrA Streptococcus pneumoniae R6

50.729

90.501

0.459

Multiple sequence alignment