Detailed information NTG0533209

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: JQR77_RS05345
• Genome accession: NZ_CP069275
• Coordinates: 1034141..1034848 (-)
• Length: 235 a.a.
• NCBI ID: WP_011681206.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain EG007
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1029141..1039848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JQR77_RS05320 (JQR77_05315)	yidA	1029493..1030302 (+)	810	WP_011226081.1	sugar-phosphatase	-
JQR77_RS05325 (JQR77_05320)	-	1030304..1031518 (+)	1215	WP_002953123.1	aminoacyltransferase	-
JQR77_RS05330 (JQR77_05325)	-	1031570..1031931 (-)	362	Protein_998	YbaN family protein	-
JQR77_RS05335 (JQR77_05330)	-	1031991..1032802 (-)	812	Protein_999	MBL fold metallo-hydrolase	-
JQR77_RS05340 (JQR77_05335)	vicK	1032808..1034148 (-)	1341	WP_011681205.1	cell wall metabolism sensor histidine kinase VicK	Regulator
JQR77_RS05345 (JQR77_05340)	vicR	1034141..1034848 (-)	708	WP_011681206.1	response regulator YycF	Regulator
JQR77_RS05350 (JQR77_05345)	-	1035375..1036142 (+)	768	WP_011681207.1	amino acid ABC transporter ATP-binding protein	-
JQR77_RS05355 (JQR77_05350)	-	1036154..1036987 (+)	834	WP_011681208.1	transporter substrate-binding domain-containing protein	-
JQR77_RS05360 (JQR77_05355)	-	1037005..1037703 (+)	699	WP_002953144.1	amino acid ABC transporter permease	-
JQR77_RS05365 (JQR77_05360)	-	1037715..1038365 (+)	651	WP_014608375.1	amino acid ABC transporter permease	-
JQR77_RS05370 (JQR77_05365)	endA	1038438..1039319 (-)	882	WP_011681210.1	DNA/RNA non-specific endonuclease	Machinery gene
JQR77_RS05375 (JQR77_05370)	-	1039381..1039569 (-)	189	WP_011226090.1	DNA-directed RNA polymerase subunit beta	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27058.98 Da
• Isoelectric Point: 5.0130

>NTDB_id=533209 JQR77_RS05345 WP_011681206.1 1034141..1034848(-) (vicR) [Streptococcus thermophilus strain EG007]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAKKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAVEESSNSGKQEISIGELVIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=533209 JQR77_RS05345 WP_011681206.1 1034141..1034848(-) (vicR) [Streptococcus thermophilus strain EG007]
ATGAAAAAAATTCTAGTTGTTGATGATGAAAGACCAATCTCCGATATCATCAAGTTTAACCTTACTAAGGAGGGTTATGA
AGTGGTTACGGCCTTTGATGGGCGAGAAGCTTTGGAACAATTTGAAGCTAAAAAACCAGACTTGGTTATTCTGGACTTGA
TGTTGCCTGAACTGGATGGTTTGGAAGTTGCCAAGGAAATCCGTAAAACGAGCCACACACCGATTATCATGCTTTCAGCT
AAAGATAGTGAGTTTGATAAGGTTATCGGATTAGAAATTGGGGCAGACGACTATGTGACTAAGCCATTTTCGAACCGTGA
ATTGTTGGCACGTATTAAAGCCCACTTGCGTCGTACAGAAACGATTGAAACCGCAGTAGAAGAGAGCTCTAACTCTGGCA
AACAAGAAATTTCAATTGGTGAGTTGGTTATTGTTCCGGATGCCTTTGTTGCTAAAAAACGTGGAAACGAAGTTGAGTTG
ACCCACCGTGAATTTGAGTTACTCTTCCATTTGGCAACTCATATGGGACAAGTTATGACGCGTGAACATTTGCTTGAAAC
CGTTTGGGGCTATGACTATTTTGGGGATGTTCGTACTGTGGACGTAACGATTCGTCGTCTGCGTGAAAAAATTGAAGATA
CACCTAGCCGTCCTGAATATATCTTGACGCGTCGTGGTGTCGGTTATTACATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.258	99.149	0.796
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.32	98.298	0.455
covR	Streptococcus salivarius strain HSISS4	45.299	99.574	0.451
scnR	Streptococcus mutans UA159	38.559	100	0.387