Detailed information NTG0532173

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: JOA01_RS05485
• Genome accession: NZ_CP069079
• Coordinates: 1081346..1082188 (-)
• Length: 280 a.a.
• NCBI ID: WP_130555292.1
• Uniprot ID: A0A4Q8L0M9
• Organism: Streptococcus parasuis strain BS26
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1076346..1087188

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JOA01_RS05470 (JOA01_05475)	rplL	1077848..1078210 (-)	363	WP_171989410.1	50S ribosomal protein L7/L12	-
JOA01_RS05475 (JOA01_05480)	rplJ	1078278..1078775 (-)	498	WP_217373850.1	50S ribosomal protein L10	-
JOA01_RS05480 (JOA01_05485)	topA	1079160..1081253 (-)	2094	WP_217373851.1	type I DNA topoisomerase	-
JOA01_RS05485 (JOA01_05490)	dprA	1081346..1082188 (-)	843	WP_130555292.1	DNA-processing protein DprA	Machinery gene
JOA01_RS05490 (JOA01_05495)	-	1082247..1082804 (-)	558	WP_217373852.1	sugar O-acetyltransferase	-
JOA01_RS05495 (JOA01_05500)	-	1082815..1083075 (-)	261	WP_217373853.1	metal-sensitive transcriptional regulator	-
JOA01_RS05500 (JOA01_05505)	-	1083196..1083531 (+)	336	WP_174846027.1	rhodanese-like domain-containing protein	-
JOA01_RS05505 (JOA01_05510)	-	1083528..1085183 (+)	1656	WP_217373854.1	FAD-dependent oxidoreductase	-
JOA01_RS05510 (JOA01_05515)	-	1085291..1085842 (+)	552	WP_217373855.1	DUF1836 domain-containing protein	-
JOA01_RS05515 (JOA01_05520)	-	1085832..1086482 (+)	651	WP_130555297.1	hemolysin III family protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31318.15 Da
• Isoelectric Point: 8.2169

>NTDB_id=532173 JOA01_RS05485 WP_130555292.1 1081346..1082188(-) (dprA) [Streptococcus parasuis strain BS26]
MNNFELFKWKKAGLSNLNINKVLAYQEKQGKKLTLRNVAVVSECKNPILFMENYKNLDTKACREEFNKYPSFSILDDIYP
TALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASENGIQSVQKIIKELNNRFVIVSGMARGIDTVAHIASLKNGGQTI
AVIGTGLDKVYPKENKELQHYIGKHQLVLTEYEPNAQPLKYHFPERNRIIAGLAEGLVVCEAKIRSGSLITCERALEEGR
EVYAIPGSIVDGKSDGCHHLIQEGAKCITSGLDILSDYLF

Nucleotide

• Length: 843 bp

>NTDB_id=532173 JOA01_RS05485 WP_130555292.1 1081346..1082188(-) (dprA) [Streptococcus parasuis strain BS26]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGCTTGTCCAATCTTAATATTAATAAAGTTTTGGCCTATCAAGA
AAAACAAGGTAAAAAATTAACTTTACGAAATGTCGCTGTAGTATCTGAATGTAAAAATCCAATTCTTTTCATGGAAAATT
ATAAGAATTTAGATACTAAGGCTTGCCGGGAGGAATTTAATAAGTATCCATCTTTTTCAATTTTGGATGATATTTATCCC
ACAGCTTTAAAACAAATTTATAATCCACCAGTTCTCTTATTTTATCAAGGTGATCTTGAATTACTTGAAAAATCAAAATT
GGCAGTGGTAGGTACACGCAATGCCAGTGAAAATGGCATTCAATCTGTTCAGAAAATTATCAAAGAACTCAATAATCGCT
TTGTCATTGTGAGTGGTATGGCCAGGGGGATTGATACAGTAGCTCATATTGCGAGTTTGAAAAATGGCGGACAAACCATT
GCAGTGATTGGAACAGGATTAGATAAGGTATATCCTAAGGAAAACAAGGAGTTACAACACTATATCGGAAAACATCAATT
AGTGCTAACAGAGTATGAACCAAATGCCCAGCCTTTAAAATACCATTTCCCCGAACGAAACCGCATTATTGCCGGATTGG
CTGAAGGTCTGGTGGTCTGTGAGGCAAAAATACGGTCTGGTAGCTTGATTACTTGCGAACGTGCCTTGGAAGAAGGAAGA
GAAGTTTATGCCATTCCTGGTTCTATTGTGGATGGAAAATCAGATGGCTGTCATCATTTGATACAGGAAGGGGCAAAGTG
CATTACATCAGGCTTGGACATCCTTTCAGACTATCTATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: A0A4Q8L0M9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	100	0.686
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.429	100	0.614
dprA/cilB/dalA	Streptococcus mitis SK321	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.429	100	0.614
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.429	100	0.614
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.714	100	0.607
dprA	Lactococcus lactis subsp. cremoris KW2	58.929	100	0.589
dprA	Vibrio campbellii strain DS40M4	35.739	100	0.371
dprA	Legionella pneumophila strain ERS1305867	41.393	87.143	0.361