NTDB

Overview

Name	ciaR	Type	Regulator
Locus tag	K8227_RS05315	Genome accession	NZ_CP082948
Coordinates	1085648..1086319 (-)	Length	223 a.a.
NCBI ID	WP_009909965.1	Uniprot ID	-
Organism	Streptococcus suis strain SZ1908
Function	repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1080648..1091319

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8227_RS05295 (K8227_05285)	rpsT	1081448..1081696 (+)	249	WP_012027069.1	30S ribosomal protein S20	-
K8227_RS05300 (K8227_05290)	tnpA	1081838..1082302 (-)	465	WP_012775157.1	IS200/IS605-like element ISSsu4 family transposase	-
K8227_RS05305 (K8227_05295)	-	1082716..1083945 (-)	1230	WP_012027071.1	transglutaminase domain-containing protein	-
K8227_RS05310 (K8227_05300)	ciaH	1084276..1085655 (-)	1380	WP_012027074.1	cell wall metabolism sensor histidine kinase WalK	Regulator
K8227_RS05315 (K8227_05305)	ciaR	1085648..1086319 (-)	672	WP_009909965.1	response regulator transcription factor	Regulator
K8227_RS05320 (K8227_05310)	-	1086513..1086893 (-)	381	WP_012027076.1	hypothetical protein	-
K8227_RS05325 (K8227_05315)	-	1087278..1088480 (+)	1203	WP_012775158.1	IS110 family transposase	-
K8227_RS05330 (K8227_05320)	phoU	1088682..1089338 (-)	657	WP_012028219.1	phosphate signaling complex protein PhoU	-
K8227_RS05335 (K8227_05325)	pstB	1089367..1090125 (-)	759	WP_002937614.1	phosphate ABC transporter ATP-binding protein PstB	-
K8227_RS05340 (K8227_05330)	pstB	1090137..1090940 (-)	804	WP_002940866.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

Download Length: 223 a.a. Molecular weight: 25290.00 Da Isoelectric Point: 4.2183

                                >NTDB_id=530934 K8227_RS05315 WP_009909965.1 1085648..1086319(-) (ciaR) [Streptococcus suis strain SZ1908]

MIKILLVEDDLSLSNSVFDFLDDFADVMQVFDGEEGVYEAETGVYDLILLDLMLPEKDGFQVLKELREKGVTTPVLITTA

KESLEDKGHGFELGADDYLTKPFYLEELKMRIQALLKRAGKFNENTLTFGDVTVDLSTNMTMVNGEEVELLGKEFDLLVY

FLQNQNVILPKTQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTTFGENLQTLRSVGYILKNA

Nucleotide

Download Length: 672 bp

                                >NTDB_id=530934 K8227_RS05315 WP_009909965.1 1085648..1086319(-) (ciaR) [Streptococcus suis strain SZ1908]

ATGATTAAAATATTGTTAGTGGAAGATGATTTAAGTCTATCAAATTCTGTTTTCGATTTCTTAGATGATTTTGCGGATGT

TATGCAGGTTTTTGATGGTGAAGAGGGCGTTTATGAGGCGGAAACAGGCGTTTATGATTTGATTCTTTTGGATTTAATGT

TACCTGAAAAAGACGGCTTTCAAGTCTTGAAAGAGTTACGTGAAAAGGGGGTTACGACACCAGTTCTGATTACAACAGCC

AAGGAAAGTCTAGAGGATAAAGGCCATGGTTTTGAATTGGGGGCTGATGACTATTTGACAAAACCGTTTTATTTAGAAGA

ATTGAAGATGCGAATTCAAGCTCTATTAAAACGAGCGGGTAAGTTTAATGAAAACACACTAACCTTTGGAGATGTGACAG

TTGACCTATCTACAAATATGACGATGGTAAATGGCGAAGAAGTTGAACTGTTAGGAAAAGAATTTGATCTACTAGTTTAT

TTCTTGCAAAATCAAAATGTTATTTTGCCAAAAACACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACTACAAT

TTCAGTAGTAGAGGTATATGTTTCTAAAATTAGGAAAAAGTTGAAAGGAACGACTTTTGGGGAAAATCTTCAAACCCTGC

GTAGTGTCGGGTACATTCTAAAAAATGCCTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
ciaR	Streptococcus mutans UA159	90.135	100	0.901
ciaR	Streptococcus pneumoniae Rx1	88.341	100	0.883
ciaR	Streptococcus pneumoniae D39	88.341	100	0.883
ciaR	Streptococcus pneumoniae R6	88.341	100	0.883
ciaR	Streptococcus pneumoniae TIGR4	88.341	100	0.883
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.496	100	0.39
vicR	Streptococcus mutans UA159	35.47	100	0.372
covR	Streptococcus salivarius strain HSISS4	35.841	100	0.363

Detailed information NTG0530934