Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   LLUC073_RS08060 Genome accession   NZ_CP068698
Coordinates   1559750..1560442 (-) Length   230 a.a.
NCBI ID   WP_282670754.1    Uniprot ID   -
Organism   Lactococcus cremoris strain UC073     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1554750..1565442
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLUC073_RS08040 (LLUC073_07840) murD 1554897..1556246 (-) 1350 WP_282670751.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLUC073_RS08045 (LLUC073_07845) - 1556415..1556756 (-) 342 WP_282670752.1 P-II family nitrogen regulator -
  LLUC073_RS08050 (LLUC073_07850) - 1556838..1558079 (-) 1242 WP_282670753.1 ammonium transporter -
  LLUC073_RS08055 (LLUC073_07855) covS 1558265..1559737 (-) 1473 WP_021037558.1 HAMP domain-containing histidine kinase Regulator
  LLUC073_RS08060 (LLUC073_07860) covR 1559750..1560442 (-) 693 WP_282670754.1 response regulator transcription factor Regulator
  LLUC073_RS08065 (LLUC073_07865) - 1560599..1561129 (-) 531 WP_011834860.1 DUF177 domain-containing protein -
  LLUC073_RS08070 (LLUC073_07870) - 1561262..1561507 (-) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLUC073_RS08075 (LLUC073_07875) - 1561831..1562193 (-) 363 WP_282670755.1 TIGR02328 family protein -
  LLUC073_RS08080 (LLUC073_07880) - 1562430..1563341 (-) 912 WP_011676635.1 CHAP domain-containing protein -
  LLUC073_RS08085 (LLUC073_07885) - 1563398..1564287 (-) 890 Protein_1573 IS982 family transposase -
  LLUC073_RS08090 (LLUC073_07890) - 1564440..1565276 (-) 837 WP_011834858.1 metallophosphoesterase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26640.31 Da        Isoelectric Point: 5.1273

>NTDB_id=530468 LLUC073_RS08060 WP_282670754.1 1559750..1560442(-) (covR) [Lactococcus cremoris strain UC073]
MASKKILIIEDEKNLARFVSLELEHEGYATEIKDNGRSGLEEATSKDYDLILLDLMLPELDGFEVARRLRKEKDTPIIMM
TARDSTMDRVAGLDIGADDYITKPFAIEELLARVRAFFRREEHGHAVERAENTSFRDLVIDKTNRSVHRGKKVIDLTRRE
YDLLLTLMQNVGDVVTREHLVSQVWGYEEGTETNVVDVYIRYLRNKIDVEGQDSYIQTVRGLGYVMRERK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=530468 LLUC073_RS08060 WP_282670754.1 1559750..1560442(-) (covR) [Lactococcus cremoris strain UC073]
ATGGCATCAAAGAAAATTTTGATTATTGAGGATGAAAAGAATTTAGCTCGTTTCGTCTCATTAGAATTAGAGCATGAAGG
CTATGCCACTGAGATTAAAGATAACGGACGTTCTGGGCTTGAAGAAGCAACTTCAAAAGATTATGATTTAATCTTGCTTG
ATTTGATGCTTCCTGAACTTGATGGTTTTGAAGTTGCCCGCCGTTTGCGCAAAGAAAAAGATACTCCAATTATTATGATG
ACCGCGCGTGATTCAACAATGGACCGTGTTGCCGGTCTTGATATTGGAGCAGATGATTATATTACTAAGCCTTTTGCGAT
TGAAGAACTTTTGGCTCGTGTTCGTGCATTCTTCCGTCGTGAAGAACATGGTCATGCTGTAGAACGTGCTGAAAACACTT
CTTTTCGTGATCTTGTAATTGACAAAACAAATCGTAGCGTTCACCGCGGTAAAAAAGTAATTGATTTGACGCGTCGTGAA
TACGATCTTCTTTTGACGTTGATGCAAAATGTTGGGGATGTTGTCACTCGCGAACATTTAGTTTCACAAGTTTGGGGATA
TGAAGAAGGAACGGAAACAAATGTTGTTGATGTATATATCCGCTATCTTAGAAATAAAATTGATGTTGAAGGACAAGACA
GCTATATTCAAACCGTTCGTGGTTTGGGTTATGTGATGCGTGAACGCAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)

Response regulator receiver domain (Response_reg)

(6-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

99.13

100

0.991
  covR Streptococcus salivarius strain HSISS4

67.982

99.13

0.674
  vicR Streptococcus mutans UA159

46.552

100

0.47
  micA Streptococcus pneumoniae Cp1015

43.478

100

0.435
  ciaR Streptococcus mutans UA159

37.168

98.261

0.365