Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   I6I40_RS05680 Genome accession   NZ_CP068136
Coordinates   1214383..1215099 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain FDAARGOS_1083     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1209383..1220099
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I40_RS05665 (I6I40_05665) - 1210664..1211617 (+) 954 WP_002457062.1 LacI family DNA-binding transcriptional regulator -
  I6I40_RS05670 (I6I40_05670) - 1211877..1213349 (+) 1473 WP_077755919.1 sucrose-6-phosphate hydrolase -
  I6I40_RS05675 (I6I40_05675) - 1213356..1214315 (+) 960 WP_077755920.1 carbohydrate kinase family protein -
  I6I40_RS05680 (I6I40_05680) agrA 1214383..1215099 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  I6I40_RS05685 (I6I40_05685) agrC 1215116..1216405 (-) 1290 WP_002447514.1 quorum-sensing sensor histidine kinase AgrC -
  I6I40_RS05690 (I6I40_05690) agrD 1216430..1216570 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide AgrD -
  I6I40_RS05695 (I6I40_05695) - 1216576..1217139 (-) 564 WP_002495668.1 accessory gene regulator AgrB -
  I6I40_RS05700 (I6I40_05700) hld 1217456..1217533 (+) 78 WP_002494082.1 delta-hemolysin -
  I6I40_RS05705 (I6I40_05705) - 1217913..1218698 (-) 786 WP_002495667.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=527436 I6I40_RS05680 WP_002447515.1 1214383..1215099(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1083]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=527436 I6I40_RS05680 WP_002447515.1 1214383..1215099(-) (agrA) [Staphylococcus epidermidis strain FDAARGOS_1083]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGGCATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374