Detailed information NTG0527436

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: K6973_RS03010
• Genome accession: NZ_CP082206
• Coordinates: 559199..561352 (-)
• Length: 717 a.a.
• NCBI ID: WP_222819557.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae strain DY107
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 554199..566352

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6973_RS02990 (K6973_02990)	comE/blpR	555377..556126 (+)	750	WP_129556053.1	response regulator transcription factor	Regulator
K6973_RS02995 (K6973_02995)	-	556127..557461 (+)	1335	WP_222819556.1	GHKL domain-containing protein	-
K6973_RS03000 (K6973_03000)	-	557609..557734 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
K6973_RS03005 (K6973_03005)	-	557825..559188 (-)	1364	Protein_541	bacteriocin secretion accessory protein	-
K6973_RS03010 (K6973_03010)	comA/nlmT	559199..561352 (-)	2154	WP_222819557.1	peptide cleavage/export ABC transporter	Regulator
K6973_RS03015 (K6973_03015)	-	561433..562538 (+)	1106	WP_222819558.1	IS3 family transposase	-
K6973_RS03020 (K6973_03020)	-	562854..563078 (+)	225	WP_015057385.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
K6973_RS03025 (K6973_03025)	-	563101..563421 (+)	321	WP_030127173.1	hypothetical protein	-
K6973_RS03030 (K6973_03030)	-	563656..564066 (+)	411	WP_222819559.1	hypothetical protein	-
K6973_RS03035 (K6973_03035)	-	564313..564560 (+)	248	Protein_547	hypothetical protein	-
K6973_RS03040 (K6973_03040)	-	564582..564828 (+)	247	Protein_548	lysostaphin resistance A-like protein	-
K6973_RS03045 (K6973_03045)	-	565044..565787 (+)	744	Protein_549	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80630.57 Da
• Isoelectric Point: 6.8706

>NTDB_id=527436 K6973_RS03010 WP_222819557.1 559199..561352(-) (comA/nlmT) [Streptococcus dysgalactiae strain DY107]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVVYQNKKNYLIIGDPDPTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISESGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=527436 K6973_RS03010 WP_222819557.1 559199..561352(-) (comA/nlmT) [Streptococcus dysgalactiae strain DY107]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGCA
TCGTCAAAGCTGCCAAATTAATGGGATTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCGTCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACCCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATTTC
ACGGTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCTTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACCAAACTTCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAATTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGAATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCGCTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGCA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter (ABC_tran) (500-649)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.727	99.721	0.725
comA	Streptococcus mitis NCTC 12261	67.507	99.582	0.672
comA	Streptococcus mitis SK321	67.087	99.582	0.668
comA	Streptococcus pneumoniae Rx1	67.087	99.582	0.668
comA	Streptococcus pneumoniae D39	67.087	99.582	0.668
comA	Streptococcus pneumoniae R6	67.087	99.582	0.668
comA	Streptococcus pneumoniae TIGR4	66.807	99.582	0.665
comA	Streptococcus gordonii str. Challis substr. CH1	65.877	100	0.66