Detailed information NTG0527145

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: K6972_RS04985
• Genome accession: NZ_CP082203
• Coordinates: 994561..995403 (+)
• Length: 280 a.a.
• NCBI ID: WP_222812952.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NJ3
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 989561..1000403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6972_RS04950 (K6972_04950)	ylqF	989661..990512 (+)	852	WP_044762865.1	ribosome biogenesis GTPase YlqF	-
K6972_RS04955 (K6972_04955)	-	990499..991272 (+)	774	WP_222812948.1	ribonuclease HII	-
K6972_RS04960 (K6972_04960)	-	991275..992285 (+)	1011	WP_222812949.1	YdcF family protein	-
K6972_RS04965 (K6972_04965)	-	992319..992969 (-)	651	WP_136581275.1	hemolysin III family protein	-
K6972_RS04970 (K6972_04970)	-	992959..993405 (-)	447	WP_136581276.1	DUF1836 domain-containing protein	-
K6972_RS04975 (K6972_04975)	-	993502..993813 (-)	312	WP_222812950.1	rhodanese-like domain-containing protein	-
K6972_RS04980 (K6972_04980)	-	993943..994500 (+)	558	WP_222812951.1	sugar O-acetyltransferase	-
K6972_RS04985 (K6972_04985)	dprA	994561..995403 (+)	843	WP_222812952.1	DNA-processing protein DprA	Machinery gene
K6972_RS04990 (K6972_04990)	topA	995496..997589 (+)	2094	WP_024407141.1	type I DNA topoisomerase	-
K6972_RS04995 (K6972_04995)	rplJ	998016..998510 (+)	495	WP_002936486.1	50S ribosomal protein L10	-
K6972_RS05000 (K6972_05000)	rplL	998576..998941 (+)	366	WP_002936483.1	50S ribosomal protein L7/L12	-
K6972_RS05005 (K6972_05005)	-	999066..999815 (+)	750	WP_222812953.1	HAD family hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31301.22 Da
• Isoelectric Point: 8.6515

>NTDB_id=527145 K6972_RS04985 WP_222812952.1 994561..995403(+) (dprA) [Streptococcus suis strain NJ3]
MNNFELFKWKKAGLTNLNINKVLAYQEKHGKKLTLRNVAVVSECKNPVLFMENYKNLDTKACREEFNKYPSFSILDDIYP
LALKQIYNPPVLLFYQGDLELLEKSKLAVVGTRNASKNGIQSVQKIIKELNNRFVIVSGLARGIDTAAHIASLKNGGQTI
AVIGTGLDKVYPKENKDLQTYIGKHHLVLTEYEPGAQPLKYHFPERNRIIAGLVEGLVVCEAKMRSGSLITCERALEEGR
EVYAIPGSIMDGKSDGCHHLIQEGAKCITSGLDIISEYQF

Nucleotide

• Length: 843 bp

>NTDB_id=527145 K6972_RS04985 WP_222812952.1 994561..995403(+) (dprA) [Streptococcus suis strain NJ3]
ATGAATAATTTTGAATTGTTTAAATGGAAAAAAGCAGGTTTGACCAATCTTAACATTAATAAAGTTTTGGCCTATCAAGA
AAAACACGGTAAAAAATTGACCTTACGCAATGTCGCTGTAGTGTCTGAATGTAAAAATCCTGTGCTATTTATGGAAAATT
ATAAGAATCTAGATACAAAAGCCTGTCGCGAGGAATTTAATAAGTATCCATCATTTTCAATTTTAGATGACATCTATCCT
TTGGCGCTCAAACAGATTTACAATCCACCTGTACTTTTGTTTTATCAAGGGGATTTAGAATTGCTAGAAAAATCAAAGCT
GGCAGTTGTTGGTACACGAAATGCCAGTAAAAATGGTATCCAATCTGTTCAGAAAATTATCAAAGAACTCAACAATCGTT
TTGTCATTGTCAGTGGTTTGGCAAGAGGAATTGATACGGCTGCCCACATCGCCAGTCTGAAAAATGGAGGCCAAACCATT
GCTGTAATTGGAACAGGTTTGGATAAGGTCTATCCCAAAGAAAACAAGGACTTGCAGACCTACATTGGCAAACACCATTT
AGTATTAACAGAGTATGAACCGGGTGCCCAGCCACTCAAATACCATTTCCCAGAACGTAACCGCATCATTGCTGGGTTGG
TAGAAGGTCTGGTGGTTTGCGAGGCAAAAATGCGGTCTGGTAGCTTGATTACTTGCGAACGTGCCTTGGAAGAAGGAAGG
GAAGTCTATGCCATTCCTGGTTCCATTATGGACGGAAAATCAGATGGTTGTCATCATCTGATTCAAGAGGGGGCAAAGTG
CATCACATCAGGCTTGGACATCATTTCTGAGTATCAATTTTAA

Domains

Predicted by InterProScan.

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70	100	0.7
dprA/cilB/dalA	Streptococcus mitis SK321	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae D39	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae R6	63.929	100	0.639
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	63.929	100	0.639
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	63.214	100	0.632
dprA	Lactococcus lactis subsp. cremoris KW2	59.643	100	0.596
dprA	Bacillus subtilis subsp. subtilis str. 168	51.244	71.786	0.368
dprA	Legionella pneumophila strain ERS1305867	40.891	88.214	0.361