Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   K6976_RS00375 Genome accession   NZ_CP082202
Coordinates   62109..63008 (+) Length   299 a.a.
NCBI ID   WP_141597428.1    Uniprot ID   -
Organism   Streptococcus suis strain SS389     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 57109..68008
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6976_RS00345 (K6976_00345) - 57673..58350 (-) 678 WP_222759586.1 amino acid ABC transporter permease -
  K6976_RS00350 (K6976_00350) - 58331..58990 (-) 660 WP_074391045.1 amino acid ABC transporter permease -
  K6976_RS00355 (K6976_00355) ruvB 59118..60116 (+) 999 WP_222759588.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  K6976_RS00360 (K6976_00360) - 60128..60862 (+) 735 WP_222759590.1 GNAT family N-acetyltransferase -
  K6976_RS00365 (K6976_00365) - 60864..61499 (+) 636 WP_222759592.1 HAD-IA family hydrolase -
  K6976_RS00370 (K6976_00370) tnpA 61514..61895 (+) 382 Protein_54 IS200/IS605 family transposase -
  K6976_RS00375 (K6976_00375) comR 62109..63008 (+) 900 WP_141597428.1 helix-turn-helix domain-containing protein Regulator
  K6976_RS00380 (K6976_00380) - 63216..64436 (+) 1221 WP_222759593.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  K6976_RS00385 (K6976_00385) - 64627..66150 (+) 1524 WP_222759595.1 quinol oxidase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35131.06 Da        Isoelectric Point: 4.5433

>NTDB_id=527005 K6976_RS00375 WP_141597428.1 62109..63008(+) (comR) [Streptococcus suis strain SS389]
MNDKEFGQRVRQLRETASLTREQFCGDELELSVRQLTRIEAGTSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEELVEKRDAIMTEIYDDYYDDLPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKQKYEVND
LLIIRLQLEYVRLSSSDSEIFGQFLKIIEYLHGQIDIINSSDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQLT
QDFQKKPIVSVLKWKYALFVNKDRGEAEKHYLDAMLFAKLIENRELEEKIEEDWKVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=527005 K6976_RS00375 WP_141597428.1 62109..63008(+) (comR) [Streptococcus suis strain SS389]
ATGAACGATAAGGAATTTGGACAACGTGTACGTCAACTTCGAGAAACCGCTAGTCTGACACGTGAACAGTTTTGCGGTGA
CGAACTTGAGCTCTCCGTCCGCCAATTAACCCGTATCGAAGCAGGTACTTCTAAGCCGACTTTTTCAAAAATCCAATATA
TCGCAACCCGATTAGGGATGGGACTATATGAGCTTATGCCTGATTATGTATCCTTGCCAGAAAGATACTCCAAGCTGAAA
TTTGATGTCCTCCGTACACCGACTTATGGTAATGAGGAATTAGTTGAAAAACGTGATGCTATCATGACGGAAATCTATGA
TGATTATTATGATGACTTGCCTGAGGAGGAGAAAATAGCGATTGATGCCATTCAATCCCGAATTGATACCTTAGAGTCAG
GGACAGCAGGCTTTGGAAAAGAGATACTGGAAGATTACTTTGAACAAATTTTTCGAAAACAAAAGTACGAAGTGAATGAT
TTGCTGATTATTAGGCTCCAGCTTGAATACGTTAGATTATCCAGTAGTGACTCAGAAATATTTGGACAGTTTTTGAAAAT
TATAGAATATTTACATGGACAAATTGATATTATCAATTCAAGTGATTTATTTGTTCTAAGAGATACATTGTTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTATGAACCAATACCAAAGATATTCGACAGTGTAGATAAAATTATACAGTTAACA
CAAGATTTTCAGAAAAAGCCAATTGTCAGCGTGTTGAAATGGAAGTACGCACTTTTTGTAAATAAGGATAGAGGTGAGGC
TGAAAAGCATTATCTAGATGCGATGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAGGAGAAGATTGAAGAAGATT
GGAAAGTTGACAATCAATAA

Domains

Predicted by InterProScan.

Helix-turn-helix domain (HTH_31)

(5-60)

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

91.973

100

0.92
  comR Streptococcus suis 05ZYH33

91.973

100

0.92
  comR Streptococcus suis D9

60.133

100

0.605
  comR Streptococcus mutans UA159

45.485

100

0.455
  comR Streptococcus infantarius subsp. infantarius ATCC BAA-102

38.144

97.324

0.371
  comR Streptococcus pyogenes MGAS315

37.037

99.331

0.368