Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6J12_RS02390 Genome accession   NZ_CP068060
Coordinates   496969..497670 (+) Length   233 a.a.
NCBI ID   WP_003035055.1    Uniprot ID   -
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 491969..502670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS02370 (I6J12_02370) ccpA 492812..493816 (+) 1005 WP_003035075.1 catabolite control protein A Regulator
  I6J12_RS02375 (I6J12_02375) - 493996..494994 (+) 999 WP_020999537.1 glycosyltransferase family 4 protein -
  I6J12_RS02380 (I6J12_02380) - 494996..496309 (+) 1314 WP_003035045.1 glycosyltransferase family 4 protein -
  I6J12_RS02385 (I6J12_02385) - 496336..496668 (+) 333 WP_003035050.1 hypothetical protein -
  I6J12_RS02390 (I6J12_02390) micA 496969..497670 (+) 702 WP_003035055.1 response regulator YycF Regulator
  I6J12_RS02395 (I6J12_02395) micB 497663..499015 (+) 1353 WP_003034973.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6J12_RS02400 (I6J12_02400) vicX 499017..499820 (+) 804 WP_003034882.1 MBL fold metallo-hydrolase Regulator
  I6J12_RS02405 (I6J12_02405) - 499829..500188 (+) 360 Protein_476 YbaN family protein -
  I6J12_RS02410 (I6J12_02410) rnc 500571..501269 (+) 699 WP_003035086.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26868.85 Da        Isoelectric Point: 4.7415

>NTDB_id=526792 I6J12_RS02390 WP_003035055.1 496969..497670(+) (micA) [Streptococcus anginosus strain FDAARGOS_1155]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=526792 I6J12_RS02390 WP_003035055.1 496969..497670(+) (micA) [Streptococcus anginosus strain FDAARGOS_1155]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGATAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCACGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTAATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGATATGATTATTTTGGAGATGTTCGGACTGTTGATGTGACAATTCGCCGTTTGAGAGAGAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGCGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

98.283

0.446
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  scnR Streptococcus mutans UA159

36.052

100

0.361