Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   I6J12_RS02395 Genome accession   NZ_CP068060
Coordinates   497663..499015 (+) Length   450 a.a.
NCBI ID   WP_003034973.1    Uniprot ID   I0SHY4
Organism   Streptococcus anginosus strain FDAARGOS_1155     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 492663..504015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J12_RS02370 (I6J12_02370) ccpA 492812..493816 (+) 1005 WP_003035075.1 catabolite control protein A Regulator
  I6J12_RS02375 (I6J12_02375) - 493996..494994 (+) 999 WP_020999537.1 glycosyltransferase family 4 protein -
  I6J12_RS02380 (I6J12_02380) - 494996..496309 (+) 1314 WP_003035045.1 glycosyltransferase family 4 protein -
  I6J12_RS02385 (I6J12_02385) - 496336..496668 (+) 333 WP_003035050.1 hypothetical protein -
  I6J12_RS02390 (I6J12_02390) micA 496969..497670 (+) 702 WP_003035055.1 response regulator YycF Regulator
  I6J12_RS02395 (I6J12_02395) micB 497663..499015 (+) 1353 WP_003034973.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6J12_RS02400 (I6J12_02400) vicX 499017..499820 (+) 804 WP_003034882.1 MBL fold metallo-hydrolase Regulator
  I6J12_RS02405 (I6J12_02405) - 499829..500188 (+) 360 Protein_476 YbaN family protein -
  I6J12_RS02410 (I6J12_02410) rnc 500571..501269 (+) 699 WP_003035086.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51418.66 Da        Isoelectric Point: 4.6876

>NTDB_id=526793 I6J12_RS02395 WP_003034973.1 497663..499015(+) (micB) [Streptococcus anginosus strain FDAARGOS_1155]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRQLNQKVKDLIAGNYSEILDVQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYDKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=526793 I6J12_RS02395 WP_003034973.1 497663..499015(+) (micB) [Streptococcus anginosus strain FDAARGOS_1155]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCAATTGAATCAAAAAGTAAAAGATTTAATTGCAG
GCAATTACTCAGAAATTTTAGATGTACAAGGTGGTCCAGAAATTACGGATATTACCAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTATCCTATATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAGTCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGACGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAGTCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACTAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCAACCAGTCATTTGGATATTGAATTGACGAATTTTACAGCTTTTATCACCTTTATTTTGA
ACCGTTTTGATAAAATCAGAAGCCAGAATGATGATAAAAAGTACGAAATTATCCGAGATTATCCGATTAACTCTATTTGG
GTCGAAATTGATACAGATAAGATGACACAGGTGATTGATAATATTATCAACAATGCCATTAAATATTCTCCTGACGGTGG
TAAGATCACAGTGAGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCCTAGGGATTCCTAAAA
AAGATTTGCCGAAAATTTTTGATAGATTTTATCGTGTAGACAAAGCAAGAAGTCGCGCCCAAGGTGGATCCGGACTGGGC
TTAGCCATTGCCAAAGAGATTATCAAGCAACATAACGGATTTATCTGGGCAAAGAGCGAGTACGACAAAGGCTCGACGTT
TACAATCGTTCTGCCATATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SHY4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

80.638

97.556

0.787
  vicK Streptococcus mutans UA159

71.149

90.889

0.647