Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6J15_RS07525 Genome accession   NZ_CP068056
Coordinates   1493895..1494569 (+) Length   224 a.a.
NCBI ID   WP_020916820.1    Uniprot ID   A0AB33ALR7
Organism   Streptococcus lutetiensis strain FDAARGOS_1158     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1488895..1499569
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6J15_RS07510 (I6J15_07510) pstB 1489511..1490269 (+) 759 WP_020916823.1 phosphate ABC transporter ATP-binding protein PstB -
  I6J15_RS07515 (I6J15_07515) phoU 1490300..1490953 (+) 654 WP_020916822.1 phosphate signaling complex protein PhoU -
  I6J15_RS07520 (I6J15_07520) - 1491184..1493727 (+) 2544 WP_111712817.1 M1 family metallopeptidase -
  I6J15_RS07525 (I6J15_07525) ciaR 1493895..1494569 (+) 675 WP_020916820.1 response regulator transcription factor Regulator
  I6J15_RS07530 (I6J15_07530) ciaH 1494559..1495887 (+) 1329 WP_020916819.1 sensor histidine kinase Regulator
  I6J15_RS07535 (I6J15_07535) - 1495956..1497304 (+) 1349 WP_407697476.1 IS3 family transposase -
  I6J15_RS07540 (I6J15_07540) rpsT 1497406..1497657 (-) 252 WP_004231769.1 30S ribosomal protein S20 -
  I6J15_RS07545 (I6J15_07545) coaA 1497733..1498653 (-) 921 WP_020916817.1 type I pantothenate kinase -
  I6J15_RS07550 (I6J15_07550) - 1498785..1499378 (+) 594 WP_061407804.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25402.03 Da        Isoelectric Point: 4.3421

>NTDB_id=526696 I6J15_RS07525 WP_020916820.1 1493895..1494569(+) (ciaR) [Streptococcus lutetiensis strain FDAARGOS_1158]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGEEGLYEAESGVYDLILLDLMLPEKGGFQVLKELREQGITTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNDNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFAKNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=526696 I6J15_RS07525 WP_020916820.1 1493895..1494569(+) (ciaR) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGATTAAGATTTTATTAGTAGAAGATGATTTGAGTTTATCGAATTCAATCTTTGATTTTTTAGACGATTTTGCGGATGT
TATGCAAGTCTTTGATGGTGAAGAAGGACTTTATGAGGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATCTGATGT
TGCCAGAAAAAGGTGGTTTCCAAGTTCTGAAAGAATTACGTGAACAAGGTATTACGACACCTGTCTTAATTATGACTGCA
AAAGAAAGCCTTGATGATAAAGGACATGGCTTTGAACTTGGTGCAGATGACTATTTGACAAAACCATTTTATCTCGAAGA
ATTAAAGATGCGCATTCAAGCGCTTTTGAAACGCTCTGGAAAATTCAACGATAATACTCTTTCTTACCACGAATTAACAG
CCGATACATCAACTAACACAACAACTGTTAACGGTGAAAAGGTTGAGTTACTAGGTAAAGAATTTGATTTACTGGTTTAT
TTCTTGCAAAACCAAAATGTTATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGATTTGATAGCGATACTACAAT
TTCAGTTGTTGAAGTTTATGTTTCTAAGATTCGCAAAAAATTAAAAGGAACAAGTTTTGCTAAAAATCTACAAACACTTC
GTAGTGTAGGATATATTCTAAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

92.825

99.554

0.924
  ciaR Streptococcus pneumoniae Rx1

87.946

100

0.879
  ciaR Streptococcus pneumoniae D39

87.946

100

0.879
  ciaR Streptococcus pneumoniae R6

87.946

100

0.879
  ciaR Streptococcus pneumoniae TIGR4

87.946

100

0.879
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.885

100

0.384
  vicR Streptococcus mutans UA159

34.764

100

0.362