Detailed information NTG0526697

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: I6J15_RS07530
• Genome accession: NZ_CP068056
• Coordinates: 1494559..1495887 (+)
• Length: 442 a.a.
• NCBI ID: WP_020916819.1
• Uniprot ID: A0AB33ALY3
• Organism: Streptococcus lutetiensis strain FDAARGOS_1158
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1496585..1497304	1494559..1495887	flank	698

Gene organization within MGE regions

Location: 1494559..1497304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6J15_RS07530 (I6J15_07530)	ciaH	1494559..1495887 (+)	1329	WP_020916819.1	sensor histidine kinase	Regulator
I6J15_RS07535 (I6J15_07535)	-	1495956..1497304 (+)	1349	WP_407697476.1	IS3 family transposase	-

Sequence

Protein

• Length: 442 a.a.
• Molecular weight: 50230.16 Da
• Isoelectric Point: 6.5190

>NTDB_id=526697 I6J15_RS07530 WP_020916819.1 1494559..1495887(+) (ciaH) [Streptococcus lutetiensis strain FDAARGOS_1158]
MLNNIHKKLSTGTFSNFFHFFIVFTGIFIIMTTIILQIMRYGLYSSVDTTLKNAADNASDYVTRTMERSDSIQSNNSFSN
SGKSKPSSNVASLSNVSVLLYDTNGKIVNAIDAFVQFGTLASSVDEDTIGEIKDEKMTTIFGQTEKYHVLTVRVYSSDYP
TIEYATFLISVSQLDEANERYVTITVSVMIIFWMISILASIYLANWMRKPILESYEKQKRFVENASHELRTPLAVLQNRL
ESLFRRPNATILDNSESIAASLDEVRNMRILTTNLLNLARRDDGLKVELEEIQPSIFNEIFENYNMIAEENGKTFVSHNF
ADRPIKTDRTLLKQLMTILFDNAIKYTDDDGFIEFTVKTTERQTILTVADNGPGISDADKAKIFDRFYRVDKARTRQKGG
FGLGLSLAKQIVDALKGDIQVKDNHPKGTIFEVRFNRYNFGK

Nucleotide

• Length: 1329 bp

>NTDB_id=526697 I6J15_RS07530 WP_020916819.1 1494559..1495887(+) (ciaH) [Streptococcus lutetiensis strain FDAARGOS_1158]
ATGCTGAATAACATACACAAAAAATTATCAACAGGAACGTTTTCTAATTTTTTCCATTTCTTCATTGTATTTACAGGAAT
TTTCATCATTATGACCACGATTATCTTGCAGATTATGCGTTATGGTCTATATTCTTCTGTAGATACTACTTTAAAAAATG
CAGCTGACAATGCAAGTGATTACGTCACACGAACAATGGAGCGTAGTGATTCCATACAATCTAATAATAGTTTTAGTAAT
TCTGGAAAAAGTAAACCCAGCTCAAATGTGGCAAGTTTAAGTAATGTCAGTGTGCTACTGTACGATACAAATGGGAAAAT
CGTAAATGCAATTGATGCGTTTGTCCAGTTCGGGACATTAGCATCTAGTGTTGATGAAGACACTATTGGTGAGATTAAAG
ATGAGAAAATGACAACTATCTTTGGTCAAACCGAAAAATACCATGTTTTAACGGTTAGAGTGTATAGTAGTGACTATCCA
ACGATTGAATACGCGACTTTCTTAATCAGTGTTAGTCAGCTTGATGAGGCAAACGAACGTTATGTAACCATAACAGTTTC
AGTCATGATTATTTTCTGGATGATTTCAATTTTAGCAAGTATTTACTTGGCAAATTGGATGCGTAAACCAATTTTAGAAA
GTTATGAAAAACAAAAGCGTTTTGTTGAAAATGCTAGTCACGAATTAAGAACGCCTTTAGCGGTGCTTCAAAACCGACTT
GAAAGTCTTTTTAGACGACCGAATGCAACAATTCTTGATAACAGTGAAAGTATTGCAGCGAGTCTTGACGAAGTTCGTAA
TATGCGTATTTTAACAACCAATCTTTTGAATCTTGCTAGGCGAGATGATGGATTGAAGGTTGAATTAGAAGAAATCCAAC
CTTCAATATTTAATGAAATTTTTGAGAATTACAACATGATTGCCGAAGAAAACGGTAAAACTTTTGTTTCTCATAATTTT
GCGGATCGTCCGATAAAAACTGATCGCACCTTGCTTAAACAATTGATGACAATCTTGTTTGATAATGCGATTAAGTACAC
TGATGATGACGGTTTTATTGAATTTACGGTTAAAACAACAGAACGCCAGACTATTCTAACCGTTGCTGATAATGGACCGG
GTATTAGTGACGCCGATAAAGCGAAAATTTTTGATCGCTTTTATCGCGTTGATAAGGCAAGGACACGTCAAAAAGGTGGC
TTTGGGCTTGGGCTATCTTTAGCTAAACAAATTGTTGATGCCTTAAAAGGTGATATTCAAGTTAAGGATAATCATCCAAA
AGGAACCATATTTGAAGTTCGTTTTAACCGATATAATTTTGGTAAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (218-284)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (328-435)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	59.77	98.416	0.588
ciaH	Streptococcus pneumoniae Rx1	52.403	98.869	0.518
ciaH	Streptococcus pneumoniae D39	52.403	98.869	0.518
ciaH	Streptococcus pneumoniae R6	52.403	98.869	0.518
ciaH	Streptococcus pneumoniae TIGR4	52.403	98.869	0.518