Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   JJN14_RS05420 Genome accession   NZ_CP067992
Coordinates   1116194..1117042 (-) Length   282 a.a.
NCBI ID   WP_201058064.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V7-A3     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Genomic Context

Location: 1111194..1122042
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JJN14_RS05400 (JJN14_05400) - 1112098..1112754 (-) 657 WP_201058061.1 MmcQ/YjbR family DNA-binding protein -
  JJN14_RS05405 (JJN14_05405) - 1112798..1113430 (-) 633 WP_201058062.1 copper homeostasis protein CutC -
  JJN14_RS05410 (JJN14_05410) - 1113524..1113883 (-) 360 WP_001220352.1 YbaN family protein -
  JJN14_RS05415 (JJN14_05415) topA 1113989..1116076 (-) 2088 WP_201058063.1 type I DNA topoisomerase -
  JJN14_RS05420 (JJN14_05420) dprA/cilB/dalA 1116194..1117042 (-) 849 WP_201058064.1 DNA-processing protein DprA Machinery gene
  JJN14_RS05425 (JJN14_05425) - 1117130..1117819 (-) 690 WP_201058065.1 sugar phosphate nucleotidyltransferase -
  JJN14_RS05430 (JJN14_05430) - 1117831..1118709 (-) 879 WP_201058066.1 DMT family transporter -
  JJN14_RS05435 (JJN14_05435) licA 1118699..1119568 (-) 870 WP_201058067.1 choline kinase LicA -
  JJN14_RS05440 (JJN14_05440) - 1119585..1120607 (-) 1023 WP_049488776.1 ribitol-5-phosphate dehydrogenase -
  JJN14_RS05445 (JJN14_05445) - 1120612..1121319 (-) 708 WP_004259627.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase -
  JJN14_RS05450 (JJN14_05450) tatA 1121655..1121825 (-) 171 WP_020902402.1 twin-arginine translocase TatA/TatE family subunit -

Sequence

Protein


Download         Length: 282 a.a.        Molecular weight: 31059.72 Da        Isoelectric Point: 5.2107

>NTDB_id=526156 JJN14_RS05420 WP_201058064.1 1116194..1117042(-) (dprA/cilB/dalA) [Streptococcus mitis strain S022-V7-A3]
MKITNYEIYKLKKSGLTNQQVLKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLEKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQSGGK
TIAVIGTGLDVIYPKANKRLQDYISNDHLVISEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide


Download         Length: 849 bp        

>NTDB_id=526156 JJN14_RS05420 WP_201058064.1 1116194..1117042(-) (dprA/cilB/dalA) [Streptococcus mitis strain S022-V7-A3]
ATGAAAATTACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGGTTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGAAATCCAGCTGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGGAGAAAGAATTTCAAAAATTTCCATCTTTCTCTATTTTAGACGACTGT
TACCCTTGGGACCTGAGTGAAATTTATGATGCGCCTGTGCTTTTATTTTACAAGGGAAATCTGGATCTCTTGAAATTTCC
AAAAGTAGCGGTTGTGGGTAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTAAGTGGTCTTGCTAAGGGCATTGATACAGCAGCTCATATGGCAGCTCTCCAGAGTGGTGGCAAA
ACCATTGCAGTGATTGGAACAGGGCTGGATGTGATTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCAGCAATGA
CCATCTGGTTATCAGTGAATATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGCTCAGGTAGTCTTATTACCTGTGAGCGAGCAATGGAAGAA
GGGCGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCTGATGGATGTCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)

DNA recombination-mediator protein A (DNA_processg_A)

(75-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

97.872

100

0.979
  dprA/cilB/dalA Streptococcus pneumoniae D39

97.872

100

0.979
  dprA/cilB/dalA Streptococcus pneumoniae R6

97.872

100

0.979
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

97.872

100

0.979
  dprA/cilB/dalA Streptococcus mitis SK321

97.163

100

0.972
  dprA Streptococcus mutans UA159

62.857

99.291

0.624
  dprA Lactococcus lactis subsp. cremoris KW2

55.357

99.291

0.55
  dprA Haemophilus influenzae Rd KW20

38.577

94.681

0.365