Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   T15_RS00775 Genome accession   NC_022665
Coordinates   116271..116678 (+) Length   135 a.a.
NCBI ID   WP_011921721.1    Uniprot ID   A0A0H3MT39
Organism   Streptococcus suis T15     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 111271..121678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T15_RS00750 (T15_0115) - 112672..113037 (+) 366 WP_023369079.1 DUF1033 family protein -
  T15_RS00755 (T15_0116) - 113072..114022 (-) 951 WP_023369081.1 S66 peptidase family protein -
  T15_RS00760 (T15_0117) comGA 114108..115058 (+) 951 WP_023369082.1 competence type IV pilus ATPase ComGA Machinery gene
  T15_RS00765 (T15_0118) comGB 114970..116007 (+) 1038 WP_256786938.1 competence type IV pilus assembly protein ComGB Machinery gene
  T15_RS00770 (T15_0119) comGC 116009..116290 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  T15_RS00775 (T15_0120) comGD 116271..116678 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD Machinery gene
  T15_RS00780 (T15_0121) comGE 116650..116943 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  T15_RS00785 (T15_0122) comGF/cglF 116930..117364 (+) 435 WP_023369086.1 competence type IV pilus minor pilin ComGF Machinery gene
  T15_RS00790 (T15_0123) comGG 117342..117752 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG Machinery gene
  T15_RS00795 (T15_0124) comGH 117809..118762 (+) 954 WP_011922562.1 class I SAM-dependent methyltransferase Machinery gene
  T15_RS00800 (T15_0125) - 118812..119999 (+) 1188 WP_023369088.1 acetate kinase -
  T15_RS00805 (T15_0126) - 120314..120865 (+) 552 WP_023369090.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 135 a.a.        Molecular weight: 15367.59 Da        Isoelectric Point: 8.3926

>NTDB_id=52494 T15_RS00775 WP_011921721.1 116271..116678(+) (comGD) [Streptococcus suis T15]
MLRRKNKAFTLFESLLTLLVVSFLAVSLSGTVQTVFRSVQEEIFLWEFEAIYKDSQKLAASSHKKVNLAIGGQEVTNGYQ
AVEVPRNVEVLEEKTIQFEEDGGNSSLTKIRFHLSQKIVTYQLYIGSGRYKKTEE

Nucleotide


Download         Length: 408 bp        

>NTDB_id=52494 T15_RS00775 WP_011921721.1 116271..116678(+) (comGD) [Streptococcus suis T15]
ATGCTACGGCGAAAAAATAAGGCTTTTACCCTGTTTGAAAGCCTGCTGACCTTGTTGGTTGTCAGTTTTTTAGCTGTTTC
CTTATCAGGAACAGTACAAACGGTCTTTCGGTCTGTTCAGGAAGAAATTTTTCTCTGGGAATTTGAGGCCATCTATAAAG
ACAGTCAGAAATTAGCAGCCAGTTCCCACAAAAAAGTGAACCTTGCTATCGGTGGACAGGAGGTTACAAATGGTTATCAG
GCTGTAGAGGTGCCCAGAAACGTAGAGGTCTTAGAGGAGAAAACTATTCAGTTTGAAGAAGATGGTGGAAATTCTTCTCT
GACCAAGATTCGTTTTCACCTTAGTCAAAAAATAGTCACGTATCAATTATATATAGGGAGTGGTCGCTATAAGAAAACAG
AAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MT39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus gordonii str. Challis substr. CH1

48.031

94.074

0.452
  comGD Streptococcus mutans UA140

46.512

95.556

0.444
  comGD Streptococcus mutans UA159

46.512

95.556

0.444
  comGD/cglD Streptococcus pneumoniae TIGR4

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae R6

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae Rx1

44.961

95.556

0.43
  comGD/cglD Streptococcus pneumoniae D39

44.961

95.556

0.43
  comGD/cglD Streptococcus mitis NCTC 12261

44.186

95.556

0.422
  comGD/cglD Streptococcus mitis SK321

43.411

95.556

0.415
  comGD Lactococcus lactis subsp. cremoris KW2

39.062

94.815

0.37

Multiple sequence alignment