Detailed information NTG0520692

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: JF649_RS04620
• Genome accession: NZ_CP066541
• Coordinates: 914202..915038 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS270
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 909202..920038

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JF649_RS04590 (JF649_04585)	-	909756..910124 (+)	369	WP_010922310.1	hypothetical protein	-
JF649_RS04595 (JF649_04590)	-	910174..911085 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
JF649_RS04600 (JF649_04595)	-	911202..911852 (-)	651	WP_129321914.1	hemolysin III family protein	-
JF649_RS04605 (JF649_04600)	-	911849..912289 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
JF649_RS04610 (JF649_04605)	ylqF	912508..913356 (+)	849	WP_129321912.1	ribosome biogenesis GTPase YlqF	-
JF649_RS04615 (JF649_04610)	-	913346..914137 (+)	792	WP_011285534.1	ribonuclease HII	-
JF649_RS04620 (JF649_04615)	dprA	914202..915038 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
JF649_RS04625 (JF649_04620)	topA	915145..917274 (+)	2130	WP_115354118.1	type I DNA topoisomerase	-
JF649_RS04630 (JF649_04625)	-	917350..918207 (-)	858	Protein_865	LysR family transcriptional regulator	-
JF649_RS04635 (JF649_04630)	-	918247..918813 (+)	567	Protein_866	PTS sugar transporter subunit IIC	-
JF649_RS04640 (JF649_04635)	-	918828..919820 (+)	993	Protein_867	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=520692 JF649_RS04620 WP_111693218.1 914202..915038(+) (dprA) [Streptococcus pyogenes strain MGAS270]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=520692 JF649_RS04620 WP_111693218.1 914202..915038(+) (dprA) [Streptococcus pyogenes strain MGAS270]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367