Detailed information NTG0051862

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: SCIM_RS02805
• Genome accession: NC_018073
• Coordinates: 559766..561916 (+)
• Length: 716 a.a.
• NCBI ID: WP_004234001.1
• Uniprot ID: -
• Organism: Streptococcus intermedius JTH08
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 554766..566916

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCIM_RS02775 (SCIM_0489)	pyrH	554797..555537 (+)	741	WP_003073377.1	UMP kinase	-
SCIM_RS02780 (SCIM_0490)	frr	555541..556098 (+)	558	WP_003069936.1	ribosome recycling factor	-
SCIM_RS02785 (SCIM_0491)	cvfB	556211..557065 (+)	855	WP_004233919.1	RNA-binding virulence regulatory protein CvfB	-
SCIM_RS02790 (SCIM_0492)	holA	557125..558162 (+)	1038	WP_004234005.1	DNA polymerase III subunit delta	-
SCIM_RS02795 (SCIM_0493)	-	558233..558838 (+)	606	WP_004233738.1	superoxide dismutase	-
SCIM_RS02800 (SCIM_0494)	-	558911..559285 (-)	375	WP_003073369.1	hypothetical protein	-
SCIM_RS02805 (SCIM_0495)	comA/nlmT	559766..561916 (+)	2151	WP_004234001.1	peptide cleavage/export ABC transporter	Regulator
SCIM_RS02810 (SCIM_0496)	-	561927..563288 (+)	1362	WP_003078103.1	bacteriocin secretion accessory protein	-
SCIM_RS02815	-	563402..563536 (+)	135	WP_004233948.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
SCIM_RS10055	-	563617..564438 (-)	822	WP_231840239.1	sensor histidine kinase	-
SCIM_RS02825 (SCIM_0498)	comE/blpR	564935..565681 (-)	747	WP_037589556.1	response regulator transcription factor	Regulator
SCIM_RS02830 (SCIM_0499)	-	565850..566563 (-)	714	WP_004233848.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 716 a.a.
• Molecular weight: 80415.96 Da
• Isoelectric Point: 9.1745

>NTDB_id=51862 SCIM_RS02805 WP_004234001.1 559766..561916(+) (comA/nlmT) [Streptococcus intermedius JTH08]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTALGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKGELPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMRSTLGIVSIGLIITYILQQMMSFSRDYLLIVLSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLSILIIVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSMVNSAIIEDINGIETIKSLTSEEARYQKIDSEFVNYLDKSFTLSKYSIFQTTLKQGFQLI
LNVLILWLGAHLVISEKISIGQLITFTALLSYFTNSLESIINLQTKLQSAKVANKRLNEVYLVESEFKTKQTLTEKGFLA
GDITFHNVSYKYGFGRDTLSDINLTIKTGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGMNQIFSQKEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSPI
LILDEATSGLDVLTEKKVIDNLMGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHAELMERQGFYHHLFNK

Nucleotide

• Length: 2151 bp

>NTDB_id=51862 SCIM_RS02805 WP_004234001.1 559766..561916(+) (comA/nlmT) [Streptococcus intermedius JTH08]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTCTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTGTTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGGTGAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGATGAATACATTCCAAATCAAATGAGATCAACTCTTGGAATAGTGTCTATTGGTCTGATTATTA
CTTATATTTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTGTACTTAGTCAGCGGCTGACCATCGATGTG
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTCTATTTTGATAA
TAGTAGGAGGGGTATTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCATGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAGCTCGTTACCAAAAGATAGACAGCGAATTTG
TAAATTATTTAGATAAATCTTTTACGCTTAGTAAATATTCTATTTTTCAAACAACCCTTAAACAAGGCTTTCAATTAATT
TTAAATGTGCTTATTTTATGGCTCGGTGCGCATTTAGTTATATCTGAGAAAATCTCAATTGGGCAGCTCATCACATTTAC
GGCTCTACTTTCTTATTTTACAAATTCTCTTGAAAGTATTATTAATCTGCAAACTAAGCTGCAGTCGGCTAAGGTTGCTA
ACAAGCGGTTGAATGAAGTTTATTTAGTAGAGTCTGAATTTAAAACTAAGCAAACACTTACAGAGAAAGGTTTCTTGGCT
GGTGATATTACGTTCCATAATGTCTCCTATAAATACGGCTTTGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AACAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTTAATGGAAATGACCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAATCTTACATTAGGGATGAATCAAATATTTTCTCA
AAAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTGGCACGCGCCCTCTTAACAAAGTCACCAATT
CTTATTCTTGACGAAGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATGGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAGCGGACAAATCAGGTTATTGTTCTTGATAAAGGGCAGA
TTATTGAAACTGGATCCCACGCTGAATTGATGGAAAGACAAGGCTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (499-648)

• ABC transporter transmembrane region (ABC_membrane) (168-437)

• Peptidase C39 family (Peptidase_C39) (6-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.073	99.022	0.714
comA	Streptococcus mitis NCTC 12261	66.62	99.581	0.663
comA	Streptococcus mitis SK321	66.48	99.581	0.662
comA	Streptococcus gordonii str. Challis substr. CH1	66.059	99.581	0.658
comA	Streptococcus pneumoniae D39	65.919	99.581	0.656
comA	Streptococcus pneumoniae R6	65.919	99.581	0.656
comA	Streptococcus pneumoniae Rx1	65.919	99.581	0.656
comA	Streptococcus pneumoniae TIGR4	65.498	99.581	0.652