Detailed information NTG0518080

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: JDY60_RS07930
• Genome accession: NZ_CP066172
• Coordinates: 1656451..1658604 (-)
• Length: 717 a.a.
• NCBI ID: WP_200370595.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain SF100
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1651451..1663604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JDY60_RS07920 (JDY60_07920)	purC	1654213..1654920 (-)	708	WP_000043285.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
JDY60_RS07925 (JDY60_07925)	comB	1655089..1656438 (-)	1350	WP_084944840.1	competence pheromone export protein ComB	Regulator
JDY60_RS07930 (JDY60_07930)	comA	1656451..1658604 (-)	2154	WP_200370595.1	peptide cleavage/export ABC transporter ComA	Regulator
JDY60_RS07935 (JDY60_07935)	-	1658814..1659023 (-)	210	WP_000869801.1	hypothetical protein	-
JDY60_RS07940 (JDY60_07940)	-	1659048..1659236 (-)	189	WP_000722238.1	hypothetical protein	-
JDY60_RS09615	-	1659316..1659528 (-)	213	WP_049549866.1	hypothetical protein	-
JDY60_RS07945 (JDY60_07945)	-	1659553..1659708 (-)	156	WP_000661692.1	hypothetical protein	-
JDY60_RS07950 (JDY60_07950)	-	1659858..1660034 (-)	177	WP_000793177.1	hypothetical protein	-
JDY60_RS07955 (JDY60_07955)	-	1660047..1660196 (-)	150	WP_033629144.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
JDY60_RS07960 (JDY60_07960)	-	1660211..1660354 (-)	144	WP_042901918.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
JDY60_RS07965 (JDY60_07965)	-	1660797..1661033 (-)	237	WP_000136435.1	acyl carrier protein	-
JDY60_RS07970 (JDY60_07970)	plsX	1661039..1662031 (-)	993	WP_200370597.1	phosphate acyltransferase PlsX	-
JDY60_RS07975 (JDY60_07975)	recO	1662028..1662798 (-)	771	WP_200370599.1	DNA repair protein RecO	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80481.76 Da
• Isoelectric Point: 6.8354

>NTDB_id=518080 JDY60_RS07930 WP_200370595.1 1656451..1658604(-) (comA) [Streptococcus oralis strain SF100]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEQKTVEDLSMM
KGDMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGTHADLLAQDGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=518080 JDY60_RS07930 WP_200370595.1 1656451..1658604(-) (comA) [Streptococcus oralis strain SF100]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCTTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTAGCCAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGATTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATTTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
TATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGAG
TCAGTCTCTTTATGGCTCCGTCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCAATT
TTGCTCAAACAGCGGGGCTTGATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATCAATATCGTGGGTTCCTA
CTATCTTCAGTCCATCATTGATAGTTACGTACCAGACCAGATGCGCTCGACACTGGGTATTATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAGATTTTGTCTTATGCCCAGGAATATCTCCTACTGATACTTGGGCAACGCTTATCGATTGAC
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTGTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTGGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTGGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCCTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCCTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTAGGAGCCATTCTTGTTATGGACGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTATTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGCAGAAAACAGTCGAAGATTTGAGCATGATG
AAAGGGGATATGACCTTTAAACAAGTTCACTATAAGTATGGCTATGGGCGTGATGTCTTGTCGGATATCAATTTGACCAT
TCCACAAGGGTCTAAGATGGCTTTTGTGGGGATTTCAGGTTCGGGTAAGACCACCTTAGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAGGCCCTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGAGCAGTCGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCTCTGAATTATCAGACAG
AATTGACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATCGTGGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCATCGCTTGACCATCGCTGAGCGGACAGAAAAGGTTGTTGTTTTGGATCAGGGCA
AGATTGTCGAAGAGGGCACCCATGCAGATTTGCTTGCACAGGATGGCTTTTACGCCCATTTGGTGAATAGCTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	94.979	100	0.95
comA	Streptococcus pneumoniae Rx1	94.7	100	0.947
comA	Streptococcus pneumoniae D39	94.7	100	0.947
comA	Streptococcus pneumoniae R6	94.7	100	0.947
comA	Streptococcus mitis SK321	94.421	100	0.944
comA	Streptococcus pneumoniae TIGR4	94.282	100	0.943
comA	Streptococcus gordonii str. Challis substr. CH1	80.474	100	0.805
comA/nlmT	Streptococcus mutans UA159	64.575	100	0.646