Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   JDY60_RS07925 Genome accession   NZ_CP066172
Coordinates   1655089..1656438 (-) Length   449 a.a.
NCBI ID   WP_084944840.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1650089..1661438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS07915 (JDY60_07915) - 1650421..1654146 (-) 3726 WP_200370594.1 phosphoribosylformylglycinamidine synthase -
  JDY60_RS07920 (JDY60_07920) purC 1654213..1654920 (-) 708 WP_000043285.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  JDY60_RS07925 (JDY60_07925) comB 1655089..1656438 (-) 1350 WP_084944840.1 competence pheromone export protein ComB Regulator
  JDY60_RS07930 (JDY60_07930) comA 1656451..1658604 (-) 2154 WP_200370595.1 peptide cleavage/export ABC transporter ComA Regulator
  JDY60_RS07935 (JDY60_07935) - 1658814..1659023 (-) 210 WP_000869801.1 hypothetical protein -
  JDY60_RS07940 (JDY60_07940) - 1659048..1659236 (-) 189 WP_000722238.1 hypothetical protein -
  JDY60_RS09615 - 1659316..1659528 (-) 213 WP_049549866.1 hypothetical protein -
  JDY60_RS07945 (JDY60_07945) - 1659553..1659708 (-) 156 WP_000661692.1 hypothetical protein -
  JDY60_RS07950 (JDY60_07950) - 1659858..1660034 (-) 177 WP_000793177.1 hypothetical protein -
  JDY60_RS07955 (JDY60_07955) - 1660047..1660196 (-) 150 WP_033629144.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  JDY60_RS07960 (JDY60_07960) - 1660211..1660354 (-) 144 WP_042901918.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  JDY60_RS07965 (JDY60_07965) - 1660797..1661033 (-) 237 WP_000136435.1 acyl carrier protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49935.93 Da        Isoelectric Point: 5.5827

>NTDB_id=518079 JDY60_RS07925 WP_084944840.1 1655089..1656438(-) (comB) [Streptococcus oralis strain SF100]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLLVFLLGFAVFAEKEMSLSTRATVEPSRIIANIQSTSNQRIVGNYLEENKL
VKQGDLLVQYQQGAEAVQVEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQANGLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEEKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMAAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETHLTSEQATKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=518079 JDY60_RS07925 WP_084944840.1 1655089..1656438(-) (comB) [Streptococcus oralis strain SF100]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGCTCGTATTTCTGTTAGGATTTGCAGTTTTTGCAGAGAAGGAGATGAGTTTGTCTACCAGAGCGACAGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGCATTGTGGGCAACTATCTGGAAGAAAACAAGTTG
GTTAAGCAAGGAGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTAGAGGCATATGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGATATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTCCCAGAGGCGG
ATAAGTTTGGTTACCAAGAGATGTTTCGAGATTATCTCAGCCAAGCAAATGGTCTAAGAAGCAATGTTTCTCAGCAAAAT
GCCAGCATCTCCTCGCAGAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGAAAA
AATACGAGACTACAAAACAGCCAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTTT
ACCAGACCTATAAAAATCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGCCTAGCTACGTATCGTGTGCAATATGCAGGTTCTGGAGCTCAACAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCACTCAAGTCTCAGCACTTAGTTAAAGTCGGTCAGGAATTAACTCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAGGGAGGTCTCCTCGATAAGGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACTAGCGATTCTACCATGGCCGCAGAAGGAACCCTGCTAGCCCAGCTCTACCCATCCTTGGAAAAAGA
AGGAAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGATTCTGTCCGTTATACTA
CGACTAATGATGCCAAGAATCAAATTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAAACTGAAAAA
GGGAATTTCTTTAAAATTGAGGCGGAGACCCATCTGACTTCTGAGCAGGCTACAAAACTTCGCTATGGTTTAGAAGGTCG
TCTACAGATGATTACAGGGAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

84.152

99.777

0.84
  comB Streptococcus pneumoniae Rx1

83.259

99.777

0.831
  comB Streptococcus pneumoniae D39

83.259

99.777

0.831
  comB Streptococcus pneumoniae R6

83.259

99.777

0.831
  comB Streptococcus pneumoniae TIGR4

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.366

99.777

0.822
  comB Streptococcus gordonii str. Challis substr. CH1

54.425

100

0.548