Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I6H73_RS05510 Genome accession   NZ_CP066073
Coordinates   1077814..1078488 (-) Length   224 a.a.
NCBI ID   WP_115261943.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1072814..1083488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS05485 (I6H73_05485) - 1072999..1074276 (-) 1278 WP_003058845.1 pyrimidine-nucleoside phosphorylase -
  I6H73_RS05490 (I6H73_05490) - 1074263..1074862 (-) 600 WP_037588233.1 class I SAM-dependent methyltransferase -
  I6H73_RS05495 (I6H73_05495) coaA 1075131..1076051 (+) 921 WP_003058858.1 type I pantothenate kinase -
  I6H73_RS05500 (I6H73_05500) rpsT 1076105..1076353 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  I6H73_RS05505 (I6H73_05505) ciaH 1076511..1077821 (-) 1311 WP_003058852.1 HAMP domain-containing sensor histidine kinase Regulator
  I6H73_RS05510 (I6H73_05510) ciaR 1077814..1078488 (-) 675 WP_115261943.1 response regulator transcription factor Regulator
  I6H73_RS05515 (I6H73_05515) - 1078692..1081229 (-) 2538 WP_003057730.1 M1 family metallopeptidase -
  I6H73_RS05520 (I6H73_05520) phoU 1081430..1082083 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -
  I6H73_RS05525 (I6H73_05525) pstB 1082161..1082919 (-) 759 WP_003057749.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25650.60 Da        Isoelectric Point: 4.3728

>NTDB_id=517184 I6H73_RS05510 WP_115261943.1 1077814..1078488(-) (ciaR) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKNGFQVLKELREKDIKIPVLIMTA
KESLDDKGQGFELGADDYLTKPFYLEELKMRIQALLKRTGKFTDKNLAFGNVVVDLGQKEVQVDGRPIELLGKEFDLLVY
LLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKIRKKLKDTDFVDKLQTLRSVGYILKSHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=517184 I6H73_RS05510 WP_115261943.1 1077814..1078488(-) (ciaR) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGATCAAACTATTATTAGTAGAAGATGACTTAAGTTTATCCAATTCCATTTTCGATTTTTTGGATGATTTTGCTGATGT
CACACAAGTTTTTGATGGCGATGAAGGCTTATATGAAGCCGAAAGTGGCATTTACGATTTGATTTTACTTGACCTTATGT
TGCCAGAAAAAAATGGCTTCCAAGTCTTGAAAGAATTGCGAGAAAAAGATATTAAAATTCCTGTGTTGATTATGACAGCC
AAAGAAAGTCTAGATGATAAGGGACAGGGCTTTGAATTAGGAGCAGATGATTACCTCACTAAGCCTTTTTACCTGGAGGA
ACTCAAGATGCGAATTCAAGCCCTGTTAAAACGTACAGGGAAATTCACGGATAAAAATCTAGCCTTTGGGAATGTCGTAG
TGGATTTAGGACAAAAAGAAGTTCAAGTGGATGGCCGGCCGATAGAACTATTAGGTAAAGAGTTTGATTTGTTGGTCTAC
CTGTTACAAAATCAGAATGTTATTTTACCTAAAACACAAATTTTTGATCGCTTATGGGGTTTTGATAGCGATACGACCAT
TTCAGTAGTTGAAGTTTACGTTTCTAAAATTAGAAAAAAACTGAAAGATACAGATTTTGTGGACAAACTGCAGACATTGA
GAAGCGTGGGGTATATTCTAAAAAGCCATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

84.163

98.661

0.83
  ciaR Streptococcus pneumoniae D39

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae R6

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae Rx1

83.71

98.661

0.826
  ciaR Streptococcus pneumoniae TIGR4

83.71

98.661

0.826
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.496

100

0.388
  vicR Streptococcus mutans UA159

35.865

100

0.379