Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I6H73_RS05505 Genome accession   NZ_CP066073
Coordinates   1076511..1077821 (-) Length   436 a.a.
NCBI ID   WP_003058852.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain FDAARGOS_1016     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1071511..1082821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H73_RS05475 (I6H73_05475) - 1071945..1072334 (-) 390 WP_003058840.1 cytidine deaminase -
  I6H73_RS05480 (I6H73_05480) deoC 1072321..1072983 (-) 663 WP_003058850.1 deoxyribose-phosphate aldolase -
  I6H73_RS05485 (I6H73_05485) - 1072999..1074276 (-) 1278 WP_003058845.1 pyrimidine-nucleoside phosphorylase -
  I6H73_RS05490 (I6H73_05490) - 1074263..1074862 (-) 600 WP_037588233.1 class I SAM-dependent methyltransferase -
  I6H73_RS05495 (I6H73_05495) coaA 1075131..1076051 (+) 921 WP_003058858.1 type I pantothenate kinase -
  I6H73_RS05500 (I6H73_05500) rpsT 1076105..1076353 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  I6H73_RS05505 (I6H73_05505) ciaH 1076511..1077821 (-) 1311 WP_003058852.1 HAMP domain-containing sensor histidine kinase Regulator
  I6H73_RS05510 (I6H73_05510) ciaR 1077814..1078488 (-) 675 WP_115261943.1 response regulator transcription factor Regulator
  I6H73_RS05515 (I6H73_05515) - 1078692..1081229 (-) 2538 WP_003057730.1 M1 family metallopeptidase -
  I6H73_RS05520 (I6H73_05520) phoU 1081430..1082083 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49888.50 Da        Isoelectric Point: 8.8305

>NTDB_id=517183 I6H73_RS05505 WP_003058852.1 1076511..1077821(-) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSIDSSLISVSNNASSYANRTMARISSFYFDAVNNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=517183 I6H73_RS05505 WP_003058852.1 1076511..1077821(-) (ciaH) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTATCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGTAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

50.913

100

0.511
  ciaH Streptococcus pneumoniae D39

50.913

100

0.511
  ciaH Streptococcus pneumoniae R6

50.913

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

50.913

100

0.511