Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I6H78_RS05175 Genome accession   NZ_CP066059
Coordinates   1067825..1069174 (-) Length   449 a.a.
NCBI ID   WP_198459009.1    Uniprot ID   A0A7T4IR69
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1062825..1074174
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS05165 (I6H78_05165) - 1063022..1066747 (-) 3726 WP_198459007.1 phosphoribosylformylglycinamidine synthase -
  I6H78_RS09455 - 1066804..1066872 (-) 69 Protein_1002 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  I6H78_RS05170 (I6H78_05170) purC 1066949..1067656 (-) 708 WP_198459008.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  I6H78_RS05175 (I6H78_05175) comB 1067825..1069174 (-) 1350 WP_198459009.1 competence pheromone export protein ComB Regulator
  I6H78_RS05180 (I6H78_05180) comA 1069187..1071340 (-) 2154 WP_198459010.1 peptide cleavage/export ABC transporter ComA Regulator
  I6H78_RS05185 (I6H78_05185) - 1071550..1071759 (-) 210 WP_000869801.1 hypothetical protein -
  I6H78_RS05190 (I6H78_05190) - 1071784..1071972 (-) 189 WP_198459011.1 hypothetical protein -
  I6H78_RS05195 (I6H78_05195) - 1071982..1072149 (-) 168 WP_000415691.1 bacteriocin -
  I6H78_RS05200 (I6H78_05200) - 1072167..1072355 (-) 189 WP_084921541.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6H78_RS05205 (I6H78_05205) - 1072799..1073035 (-) 237 WP_000136435.1 acyl carrier protein -
  I6H78_RS05210 (I6H78_05210) plsX 1073042..1074034 (-) 993 WP_198459012.1 phosphate acyltransferase PlsX -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49777.73 Da        Isoelectric Point: 5.2667

>NTDB_id=516964 I6H78_RS05175 WP_198459009.1 1067825..1069174(-) (comB) [Streptococcus oralis strain FDAARGOS_1021]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLFVFLLGFAVFAEKEISLSTRATVEPSRVIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQVEAYANQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEEKIRDYKTAKSAIEKGDQLDSQNAAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARLKVGDSVRFTTSKDGNKELVLVSAITNIDATATKTEK
GNFFKIEAETSLTPEQAESLRYGSEGRLTLITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=516964 I6H78_RS05175 WP_198459009.1 1067825..1069174(-) (comB) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGTTCGTGTTTCTGTTAGGATTTGCAGTTTTTGCAGAGAAAGAGATTAGTTTGTCTACTAGAGCCACTGTCG
AACCTAGTCGGGTCATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAACTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGAGATCTACTCGTTCAGTACCAGCAAGGGGCCGAGGCTGTTCAGGTTGAAGCATACGCTAATCAGTTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGTTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGTAATGTTTCTCAACAAAAT
GCCAGCATCTCCTCACAAAATGCGGCAGCAAGTCAGAGTCAGGCCGAGATTGGCAATCTTATCAGTCAAACAGAGGAAAA
AATCCGAGACTACAAAACAGCTAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAAAATGCAGCCTACTCTTTTT
ACCAAACCTATAAAAACCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAACTAGAGTCTAGTTTAGCTACCTATCGTGTACAATATGCGGGTTCTGGAGCTCAACAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCACTCAAATCTCAGCACTTAGTTAAAGTCGGTCAGGAATTAACTCTTCTAGATCAGAAAATTTTGG
AGGCGGAATCAGGTAAGAAGGTTCAAGGAGGTCTGCTGGACAAGGGGAAGATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTCGCAGAAGGAACCCTGCTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGAAAAACTAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCAAGGCTCAAGGTCGGTGATTCTGTCCGTTTCACTA
CAAGCAAGGATGGTAATAAAGAGCTCGTTCTTGTTTCTGCGATTACGAATATTGACGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGCGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGGCG
TTTGACGCTAATCACAGGGAAGAAAAGCTATCTCCGATATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4IR69

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

80.58

99.777

0.804
  comB Streptococcus pneumoniae Rx1

80.357

99.777

0.802
  comB Streptococcus pneumoniae D39

80.357

99.777

0.802
  comB Streptococcus pneumoniae R6

80.357

99.777

0.802
  comB Streptococcus pneumoniae TIGR4

79.911

99.777

0.797
  comB Streptococcus mitis NCTC 12261

79.018

99.777

0.788
  comB Streptococcus gordonii str. Challis substr. CH1

54.204

100

0.546