Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   I6H72_RS03520 Genome accession   NZ_CP066055
Coordinates   714516..716666 (-) Length   716 a.a.
NCBI ID   WP_198458310.1    Uniprot ID   -
Organism   Streptococcus constellatus strain FDAARGOS_1015     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 709516..721666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H72_RS03495 (I6H72_03495) - 709913..710626 (+) 714 WP_048800552.1 CPBP family intramembrane glutamic endopeptidase -
  I6H72_RS03500 (I6H72_03500) comE/blpR 710795..711541 (+) 747 WP_041786327.1 response regulator transcription factor Regulator
  I6H72_RS03505 (I6H72_03505) - 711942..712853 (+) 912 WP_232619602.1 GHKL domain-containing protein -
  I6H72_RS03510 (I6H72_03510) - 712898..713047 (-) 150 WP_096362645.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I6H72_RS03515 (I6H72_03515) - 713144..714505 (-) 1362 WP_020999319.1 bacteriocin secretion accessory protein -
  I6H72_RS03520 (I6H72_03520) comA/nlmT 714516..716666 (-) 2151 WP_198458310.1 peptide cleavage/export ABC transporter Regulator
  I6H72_RS03525 (I6H72_03525) - 717147..717521 (+) 375 WP_003073369.1 hypothetical protein -
  I6H72_RS03530 (I6H72_03530) - 717584..718189 (-) 606 WP_198458311.1 superoxide dismutase -
  I6H72_RS03535 (I6H72_03535) holA 718260..719297 (-) 1038 WP_006267208.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 716 a.a.        Molecular weight: 80396.02 Da        Isoelectric Point: 9.4725

>NTDB_id=516842 I6H72_RS03520 WP_198458310.1 714516..716666(-) (comA/nlmT) [Streptococcus constellatus strain FDAARGOS_1015]
MNVKKTFVPQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTSKEGTTAFGIVQAAQEIGFETRPIQGDMSLFDMEAIP
YPFIVHVQKKAKLPHYYVIYKNTKKGLLVGDPDPSVKITKISKETFATEWTGVAIFLAPEPSYKPHKDKKNGLISLIPLI
FKQKMLVTYIVLASLLVTLINIVGSYYLQGILDEYIPNQMKSTLGIVSIGLIITYILQQMMSFSRDYLLIILSQRLTIDV
ILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDLFILIMVGGVLLLQNTNLFFLTLLAIPIYTVI
IFAFIKPFEKMNHDVMQSNSVVNSAIIEDINGIETIKSLTSEESRYQKIDSEFVDYLNKTFKLSKYSIMQTALKQGAQFI
LNVVILWVGASLAMSQKISIGQLITFNALLSYFTSPLESIINLQTKLQSAKVANNRLNEVYLVESEFKTKQVITEKNFLA
GDITFHNVSYKYGFGRDTLSDINLTIKIGDKVSLVGISGSGKTTLAKMMVHFYEPYKGQIRLNGNDLKMIDKKTLRQYIN
YLPQQAYIFSGSILENLTLGTNQIFSQEEIIRACEIAEIRSDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKSSI
LILDEATSGLDVLTEKKVIDNLIGLKDKTIIFVAHRLSISKRTNQVIVLDKGQIIETGSHTKLMERKGFYHHLFNK

Nucleotide


Download         Length: 2151 bp        

>NTDB_id=516842 I6H72_RS03520 WP_198458310.1 714516..716666(-) (comA/nlmT) [Streptococcus constellatus strain FDAARGOS_1015]
GTGAATGTTAAGAAAACATTTGTTCCTCAAATAGATGCAAGAGATTGCGGTGTCGCTGCGCTTGCTTCCATTGCAAAATA
CTATGGTTCAGACTACTCTCTTGCACATCTGAGAGAACTTGCTAAGACAAGTAAAGAAGGGACAACGGCTTTTGGAATTG
TTCAAGCAGCGCAAGAAATAGGTTTTGAGACACGACCGATTCAAGGGGATATGTCTTTATTTGATATGGAAGCTATTCCC
TATCCTTTTATCGTTCATGTTCAGAAAAAAGCTAAACTCCCACATTATTATGTTATCTATAAAAATACGAAAAAAGGTCT
GCTAGTTGGAGATCCTGACCCAAGTGTAAAAATAACCAAGATCTCAAAAGAAACATTTGCAACAGAATGGACTGGTGTTG
CTATTTTTTTAGCACCAGAACCTAGCTATAAACCACATAAGGATAAGAAAAATGGTTTGATAAGCTTAATTCCTCTTATT
TTTAAACAGAAAATGCTGGTCACCTATATTGTTTTAGCTAGTTTGCTTGTGACACTCATCAATATTGTTGGATCTTACTA
CCTACAAGGAATTTTAGACGAATACATTCCAAATCAGATGAAATCAACTCTTGGAATCGTTTCAATTGGGCTTATCATTA
CTTACATCTTGCAGCAAATGATGAGTTTTTCCAGAGATTACTTATTGATTATACTTAGTCAGCGACTAACCATCGATGTA
ATTTTATCATATATTCGACACATTTTTGAATTACCGATGTCTTTTTTTGCTACGAGACGCACTGGAGAGATTATTTCTCG
TTTTACAGATGCTAATTCCATTATTGATGCTCTCGCTTCTACAATACTTTCACTCTTTCTTGACCTTTTTATTTTGATAA
TGGTAGGAGGGGTACTATTATTACAGAATACCAACCTTTTCTTCCTCACTCTGCTTGCTATTCCTATCTATACGGTGATT
ATTTTTGCTTTTATAAAGCCTTTTGAAAAAATGAATCATGACGTCATGCAAAGCAATTCCGTGGTAAATTCTGCTATTAT
CGAAGATATTAATGGCATTGAAACCATTAAATCTTTAACAAGCGAAGAAAGTCGTTACCAAAAGATTGATAGTGAGTTTG
TCGATTATCTGAATAAGACTTTCAAGCTAAGTAAATATTCCATTATGCAGACAGCTCTCAAACAAGGAGCACAATTTATT
TTGAATGTTGTTATTCTATGGGTTGGAGCCTCTCTGGCTATGTCTCAAAAAATTTCGATTGGACAGCTGATTACTTTTAA
TGCACTCCTTTCGTATTTTACAAGTCCACTTGAAAGTATCATCAATCTGCAAACCAAGCTGCAATCGGCTAAGGTTGCCA
ACAATCGGTTGAATGAAGTCTATCTGGTAGAATCCGAATTCAAAACCAAACAAGTCATTACAGAGAAAAATTTCTTGGCT
GGTGATATTACGTTCCATAATGTTTCCTATAAGTACGGTTTCGGACGAGATACGTTATCGGATATTAACTTAACAATAAA
AATAGGAGATAAGGTGAGCTTAGTCGGCATCAGTGGTTCGGGAAAGACAACACTTGCCAAAATGATGGTTCATTTTTATG
AGCCTTATAAAGGGCAAATCCGTCTCAATGGAAATGATCTTAAAATGATTGATAAGAAGACGCTTCGTCAATATATCAAT
TATTTACCACAACAAGCCTATATTTTTAGTGGTTCTATCTTAGAAAACCTTACATTAGGGACGAATCAAATATTTTCTCA
AGAAGAGATTATTCGCGCTTGTGAAATTGCAGAAATTCGTTCGGATATTGAACAAATGCCTATGGGATATCAAACAGAAT
TGTCCGATGGAGCTGGTCTATCAGGTGGACAAAAGCAAAGAATTGCTCTAGCACGCGCCCTCTTAACAAAGTCATCAATT
CTTATTCTTGATGAGGCAACGAGCGGATTGGATGTTCTAACTGAGAAAAAGGTCATTGACAATCTGATAGGTTTAAAAGA
CAAAACGATTATTTTTGTTGCTCATCGTCTCAGCATTTCAAAACGGACAAATCAAGTGATTGTTCTTGATAAAGGACAGA
TTATTGAAACTGGTTCCCACACTAAATTGATGGAAAGAAAAGGTTTTTATCATCATTTATTTAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(499-648)

ABC transporter transmembrane region (ABC_membrane)

(168-437)

Peptidase C39 family (Peptidase_C39)

(6-141)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.073

99.022

0.714
  comA Streptococcus mitis NCTC 12261

65.919

99.581

0.656
  comA Streptococcus mitis SK321

65.778

99.581

0.655
  comA Streptococcus pneumoniae D39

65.498

99.581

0.652
  comA Streptococcus pneumoniae Rx1

65.498

99.581

0.652
  comA Streptococcus pneumoniae R6

65.498

99.581

0.652
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.581

0.651
  comA Streptococcus pneumoniae TIGR4

65.077

99.581

0.648