Detailed information NTG0516656

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: I6I32_RS05215
• Genome accession: NZ_CP066041
• Coordinates: 1068442..1070595 (-)
• Length: 717 a.a.
• NCBI ID: WP_198464219.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_1075
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1063442..1075595

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I32_RS05205 (I6I32_05205)	purC	1066204..1066911 (-)	708	WP_000043286.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
I6I32_RS05210 (I6I32_05210)	comB	1067080..1068429 (-)	1350	WP_198464218.1	competence pheromone export protein ComB	Regulator
I6I32_RS05215 (I6I32_05215)	comA	1068442..1070595 (-)	2154	WP_198464219.1	peptide cleavage/export ABC transporter ComA	Regulator
I6I32_RS05220 (I6I32_05220)	-	1070806..1071015 (-)	210	WP_000869801.1	hypothetical protein	-
I6I32_RS05225 (I6I32_05225)	-	1071040..1071228 (-)	189	WP_000722238.1	hypothetical protein	-
I6I32_RS05230 (I6I32_05230)	-	1071266..1071487 (-)	222	WP_049478100.1	hypothetical protein	-
I6I32_RS05235 (I6I32_05235)	-	1071512..1071667 (-)	156	WP_000661692.1	hypothetical protein	-
I6I32_RS05240 (I6I32_05240)	-	1071817..1071993 (-)	177	WP_186822451.1	hypothetical protein	-
I6I32_RS05245 (I6I32_05245)	-	1072006..1072155 (-)	150	WP_001052546.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6I32_RS05250 (I6I32_05250)	-	1072173..1072316 (-)	144	WP_000180838.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I6I32_RS05255 (I6I32_05255)	-	1072633..1072869 (-)	237	WP_000136435.1	acyl carrier protein	-
I6I32_RS05260 (I6I32_05260)	plsX	1072876..1073868 (-)	993	WP_198464220.1	phosphate acyltransferase PlsX	-
I6I32_RS05265 (I6I32_05265)	recO	1073865..1074635 (-)	771	WP_000616144.1	DNA repair protein RecO	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80505.85 Da
• Isoelectric Point: 7.3722

>NTDB_id=516656 I6I32_RS05215 WP_198464219.1 1068442..1070595(-) (comA) [Streptococcus oralis strain FDAARGOS_1075]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPSIKLTKISRERFAQEWTGVSIFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSML
KGEMTFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLNQGKIVEEGKHADLLAQDGFYAHLANS

Nucleotide

• Length: 2154 bp

>NTDB_id=516656 I6I32_RS05215 WP_198464219.1 1068442..1070595(-) (comA) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAATTTAGGAAAAGGCACTATCGTCCTCAGGTGGATCAGATGGATTGTGGCGTGGCTTCCTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTGGCAAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGATTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATTTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
CATTCATATCGCTGATCCAGATCCTAGTATCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAGTGGACAGGGG
TTAGTATTTTTATGGCACCATCACCGGACTATAAACCTCATAAGGAGAAAAAACAGGGACTCCTATCCTTCTTGCCGATC
TTACTCAAGCAGCGTGGCTTAATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATTAACATTGTAGGTTCTTA
TTATCTGCAGTCTATCATTGACAGTTACGTACCAGACCAGATGCGTTCGACCTTGGGCATTATCTCAATAGGACTAGTTA
TTGTCTATATTCTCCAGCAGATTTTGTCCTACGCGCAGGAATATCTCTTACTTGTTCTGGGTCAACGGTTGTCCATCGAT
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCGATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTTTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTAGCTTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTTGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCTTTTATGAAGCCGTTTGAAAAGATGAATCGAGATACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATCGAGGACATCAATGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTGGCTTATCTGAAAAAATCTTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCGCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTGGGAGCTATTCTTGTCATGGATGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGAAGAAAACGGTAGAAGATTTGAGCATGCTG
AAGGGAGAAATGACCTTCAAGCAAGTTCACTATAAGTATGGCTATGGTCGTGATGTCTTGTCGGATATCAATTTGACCAT
TCCACAAGGGTCTAAGATGGCTTTTGTGGGGATTTCGGGGTCAGGAAAGACCACCTTAGCCAAGATGATGGTTAATTTCT
ACGATCCTAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGACAAAAAGGCCTTGCGTCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGGGCGGTCGAATTGGCAGAGATTCGGGAGGATATCGAGCGCATGCCACTGAATTACCAGACAG
AATTAACTTCGGATGGGGCTGGAATTTCAGGTGGACAACGTCAGCGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCTGTCTTGATCTTGGACGAGGCGACCAGCAGTCTGGATATTTTGACAGAGAAGCGGATTGTTGATAATCTTATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGCTTGACCATCGCTGAGCGGACAGAGAAGGTTGTTGTTTTGAATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGATGGATTTTACGCCCATTTGGCGAATAGCTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis SK321	94.421	100	0.944
comA	Streptococcus mitis NCTC 12261	94.282	100	0.943
comA	Streptococcus pneumoniae D39	94.142	100	0.941
comA	Streptococcus pneumoniae R6	94.142	100	0.941
comA	Streptococcus pneumoniae Rx1	94.142	100	0.941
comA	Streptococcus pneumoniae TIGR4	93.724	100	0.937
comA	Streptococcus gordonii str. Challis substr. CH1	80.335	100	0.803
comA/nlmT	Streptococcus mutans UA159	64.575	100	0.646