Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   I6I32_RS05210 Genome accession   NZ_CP066041
Coordinates   1067080..1068429 (-) Length   449 a.a.
NCBI ID   WP_198464218.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1062080..1073429
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS05200 (I6I32_05200) - 1062422..1066147 (-) 3726 WP_198464217.1 phosphoribosylformylglycinamidine synthase -
  I6I32_RS05205 (I6I32_05205) purC 1066204..1066911 (-) 708 WP_000043286.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  I6I32_RS05210 (I6I32_05210) comB 1067080..1068429 (-) 1350 WP_198464218.1 competence pheromone export protein ComB Regulator
  I6I32_RS05215 (I6I32_05215) comA 1068442..1070595 (-) 2154 WP_198464219.1 peptide cleavage/export ABC transporter ComA Regulator
  I6I32_RS05220 (I6I32_05220) - 1070806..1071015 (-) 210 WP_000869801.1 hypothetical protein -
  I6I32_RS05225 (I6I32_05225) - 1071040..1071228 (-) 189 WP_000722238.1 hypothetical protein -
  I6I32_RS05230 (I6I32_05230) - 1071266..1071487 (-) 222 WP_049478100.1 hypothetical protein -
  I6I32_RS05235 (I6I32_05235) - 1071512..1071667 (-) 156 WP_000661692.1 hypothetical protein -
  I6I32_RS05240 (I6I32_05240) - 1071817..1071993 (-) 177 WP_186822451.1 hypothetical protein -
  I6I32_RS05245 (I6I32_05245) - 1072006..1072155 (-) 150 WP_001052546.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6I32_RS05250 (I6I32_05250) - 1072173..1072316 (-) 144 WP_000180838.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  I6I32_RS05255 (I6I32_05255) - 1072633..1072869 (-) 237 WP_000136435.1 acyl carrier protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50039.90 Da        Isoelectric Point: 5.1376

>NTDB_id=516655 I6I32_RS05210 WP_198464218.1 1067080..1068429(-) (comB) [Streptococcus oralis strain FDAARGOS_1075]
MKPEFLESAEFYNRRYHNFSSRVILPMSLLFVFLLGFSVFAEKEMSLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVQYQQGAEAVQVEAYTSQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNPAYSFYQTYKNQGEEDPQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAHATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKITASEDGVLH
LNPETSDSTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQTFLDSTITSIDATATKTEQ
GNFFKIEAETNLTSEQAEKLRYGLEGRLQMITGKKSYLRYFWDQFLNKG

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=516655 I6I32_RS05210 WP_198464218.1 1067080..1068429(-) (comB) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCACTTCTGTTCGTGTTTTTACTAGGATTTTCAGTTTTTGCAGAGAAGGAGATGAGTTTGTCTACCAGAGCAACTGTCG
AACCTAGTCGGATTATTGCCAATATCCAGTCGACTAGCAATCAACGCATTGTGGCCAACTATCTGGAAGAAAACAAGTTG
GTCAAGCAAGGAGATCTGCTCGTTCAGTACCAGCAAGGGGCGGAGGCTGTCCAGGTTGAGGCATATACCAGTCAATTGGA
GATGCTAAAGGATCAAAAAAAGCAGTTGGGGTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGTTATCAGGAGATGTTTCGAGATTATCTCAGCCAAGCTAGTAGTCTTAGGAGTAATGTTTCTCAGCAAAAT
GCCAGCATCTCTTCTCAAAATGCGGCAGCAAGTCAGAGCCAGGCCGAGATTGGCAATCTTATCAGCCAAACAGAGGATAA
AATCCGAGACTACAAAACAGCTAAGTCAGCGATTGAAAAGGGAGATCAACTGGATAGTCAGAATCCAGCCTACTCTTTCT
ATCAGACCTATAAAAACCAAGGTGAAGAAGATCCGCAAGCTAAATCGCAAGTTATTGCGCAAGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTCTAGCTACGTATCGTGTACAGTATGCGGGTTCTGGGGCTCAGCAGGCCCACGCAACGGGACTGGA
TAGTCAACTGGAATCGCTCAAGTCTCAGCACTTAGTCAAAGTTGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTAG
AAGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTACAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAAACCAGTGATTCTACAATGGTTGCAGAGGGGACCTTGCTAGCCCAACTCTATCCATCCTTGGAAAAAGA
AGGCAAAACTAAACTCACGGCTTATCTCAGTTCAAAAGATGTTGCTAGAGTCAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCCAAGAATCAAACTTTCCTGGATTCCACGATTACAAGTATTGATGCGACAGCTACAAAAACTGAACAA
GGAAATTTCTTTAAAATTGAGGCGGAGACTAATTTAACTTCGGAGCAGGCTGAAAAACTTCGCTATGGTTTAGAAGGCCG
CCTGCAGATGATCACGGGAAAGAAAAGCTATCTCCGTTATTTTTGGGATCAATTTTTGAATAAAGGGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

83.929

99.777

0.837
  comB Streptococcus pneumoniae Rx1

83.259

99.777

0.831
  comB Streptococcus pneumoniae D39

83.259

99.777

0.831
  comB Streptococcus pneumoniae R6

83.259

99.777

0.831
  comB Streptococcus pneumoniae TIGR4

82.812

99.777

0.826
  comB Streptococcus mitis NCTC 12261

82.366

99.777

0.822
  comB Streptococcus gordonii str. Challis substr. CH1

55.31

100

0.557