Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   I6I32_RS00300 Genome accession   NZ_CP066041
Coordinates   58200..58907 (+) Length   235 a.a.
NCBI ID   WP_000722058.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 53200..63907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS00275 (I6I32_00275) - 53497..54168 (+) 672 WP_000151554.1 GTP pyrophosphokinase family protein -
  I6I32_RS00280 (I6I32_00280) - 54152..54970 (+) 819 WP_000799063.1 NAD kinase -
  I6I32_RS00285 (I6I32_00285) - 54967..55863 (+) 897 WP_198464635.1 RluA family pseudouridine synthase -
  I6I32_RS00290 (I6I32_00290) pta 55907..56881 (+) 975 WP_000451583.1 phosphate acetyltransferase -
  I6I32_RS00295 (I6I32_00295) mutY 56964..58124 (+) 1161 WP_198464636.1 A/G-specific adenine glycosylase -
  I6I32_RS00300 (I6I32_00300) micA 58200..58907 (+) 708 WP_000722058.1 response regulator YycF Regulator
  I6I32_RS00305 (I6I32_00305) micB 58900..60249 (+) 1350 WP_000568720.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I6I32_RS00310 (I6I32_00310) vicX 60251..61060 (+) 810 WP_198464637.1 MBL fold metallo-hydrolase Regulator
  I6I32_RS00315 (I6I32_00315) - 61146..61919 (+) 774 WP_198464638.1 potassium channel family protein -
  I6I32_RS00320 (I6I32_00320) - 61957..62304 (-) 348 WP_000434660.1 thioredoxin -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27005.85 Da        Isoelectric Point: 4.6177

>NTDB_id=516615 I6I32_RS00300 WP_000722058.1 58200..58907(+) (micA) [Streptococcus oralis strain FDAARGOS_1075]
MKKILIVDDEKPISDIIKFNMAKEGYEVVTAFNGREAIELFEAEQPDIIILDLMLPEIDGLEVAKAIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDSQESDEKKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 708 bp        

>NTDB_id=516615 I6I32_RS00300 WP_000722058.1 58200..58907(+) (micA) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAAAAAATATTAATTGTAGATGATGAGAAACCAATCTCAGATATTATTAAGTTTAATATGGCCAAGGAAGGGTATGA
AGTTGTCACAGCTTTCAATGGTCGTGAGGCAATCGAGCTATTTGAAGCAGAGCAACCAGATATTATTATCCTCGACTTGA
TGTTACCTGAAATTGATGGTTTAGAAGTTGCTAAAGCTATTCGTAAGACTAGTAGCGTGCCAATTATCATGCTATCAGCT
AAGGATAGCGAGTTTGACAAGGTTATTGGTTTAGAGTTAGGTGCAGATGATTATGTTACAAAACCTTTCTCAAACCGTGA
GTTGCAGGCTCGTGTTAAGGCTCTTCTTCGTCGTACCGACTTGGTTTCAGTTGATAGTCAAGAGTCTGATGAGAAGAAGA
CGCAACCTTTACAAATTGGTGATTTGGAAATTGTCCCAGATGCTTACGTGGCAAAGAAATATGGTGAGGAATTAGATTTG
ACCCACCGTGAGTTTGAACTCTTGTATCACTTGGCATCTCATATTGGACAAGTGATTACGCGTGAACACTTGCTTGAGAC
TGTATGGGGTTATGACTATTTTGGTGATGTTCGTACTGTGGACGTGACCATTAGACGCTTGCGTGAGAAAATAGAAGACA
CTCCAAGTCGTCCAGAGTACATTCTCACACGTCGTGGTGTTGGATACTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

92.308

99.574

0.919
  vicR Streptococcus mutans UA159

77.447

100

0.774
  covR Streptococcus salivarius strain HSISS4

43.723

98.298

0.43
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

37.179

99.574

0.37