Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   I6H77_RS04345 Genome accession   NZ_CP066021
Coordinates   884047..884709 (+) Length   220 a.a.
NCBI ID   WP_000995723.1    Uniprot ID   A0A081R3Z6
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 879047..889709
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS04320 (I6H77_04320) tsf 879435..880475 (+) 1041 WP_000808057.1 translation elongation factor Ts -
  I6H77_RS04325 (I6H77_04325) cysK 880579..881505 (-) 927 WP_001029449.1 cysteine synthase A -
  I6H77_RS04330 (I6H77_04330) - 881602..882045 (-) 444 WP_000863903.1 PH domain-containing protein -
  I6H77_RS04335 (I6H77_04335) - 882060..882695 (-) 636 WP_000395765.1 YigZ family protein -
  I6H77_RS04340 (I6H77_04340) comFA/cflA 882752..884050 (+) 1299 WP_000867712.1 DEAD/DEAH box helicase Machinery gene
  I6H77_RS04345 (I6H77_04345) comFC/cflB 884047..884709 (+) 663 WP_000995723.1 ComF family protein Machinery gene
  I6H77_RS04350 (I6H77_04350) hpf 884789..885337 (+) 549 WP_000599114.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6H77_RS04355 (I6H77_04355) - 885419..886597 (+) 1179 WP_000656055.1 acetyl-CoA C-acetyltransferase -
  I6H77_RS04360 (I6H77_04360) - 886743..888716 (+) 1974 WP_000739979.1 DHH family phosphoesterase -
  I6H77_RS04365 (I6H77_04365) rplI 888713..889165 (+) 453 WP_000864211.1 50S ribosomal protein L9 -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25020.01 Da        Isoelectric Point: 8.1493

>NTDB_id=516472 I6H77_RS04345 WP_000995723.1 884047..884709(+) (comFC/cflB) [Streptococcus oralis strain FDAARGOS_1020]
MNCLLCGQTTKSELTFSSLFLLKDDCSYLCSACASSFERIGENYCPNCMKTGMSTKCQDCKLWCKEGIQVDHKAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASVLAEELKKYRGYQFVLIPLSPERLLERGFNQVEGLVEATGFSFKDILGKREESASSS
KSRLERLATEIPFFIKDGISFPKKILLIDDIYTTGATVNRVKRLLEEAGALEVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=516472 I6H77_RS04345 WP_000995723.1 884047..884709(+) (comFC/cflB) [Streptococcus oralis strain FDAARGOS_1020]
ATGAACTGTTTATTATGTGGCCAGACTACAAAGAGTGAGCTGACTTTTAGCAGTCTCTTCCTTTTGAAGGATGATTGCAG
TTATCTTTGCTCAGCTTGTGCTTCTAGTTTTGAGAGGATTGGTGAGAATTATTGCCCAAACTGTATGAAAACAGGCATGT
CAACTAAGTGTCAAGATTGTAAACTTTGGTGTAAAGAAGGAATTCAGGTTGATCATAAGGCAATCTTTACCTATAATCAA
GCTATGAAAGACTTTTTCAGTCGATATAAGTTTGATGGCGATTTTTTGCTTAGAAAGGTTTTTGCTTCTGTTCTTGCTGA
GGAGCTGAAAAAGTATAGAGGATATCAATTTGTGTTGATTCCCCTAAGCCCTGAAAGATTGCTTGAGAGGGGGTTTAACC
AAGTCGAAGGTTTGGTTGAGGCAACAGGCTTTTCTTTTAAAGATATATTAGGAAAAAGAGAAGAGAGCGCTAGTTCTTCT
AAAAGCCGTTTGGAAAGGTTAGCTACTGAAATTCCATTTTTTATTAAAGATGGTATCTCATTTCCTAAGAAGATTTTGCT
GATTGATGACATCTATACAACAGGGGCAACTGTGAATCGTGTGAAACGACTTTTGGAAGAAGCAGGTGCTTTGGAAGTTA
AAACTTTTTCCCTTGTAAGATAA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(183-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A081R3Z6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus mitis NCTC 12261

79.091

100

0.791
  comFC/cflB Streptococcus mitis SK321

78.182

100

0.782
  comFC/cflB Streptococcus pneumoniae D39

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae R6

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae Rx1

77.727

100

0.777
  comFC/cflB Streptococcus pneumoniae TIGR4

77.727

100

0.777
  comFC Bacillus subtilis subsp. subtilis str. 168

36.564

100

0.377