Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6H77_RS04340 Genome accession   NZ_CP066021
Coordinates   882752..884050 (+) Length   432 a.a.
NCBI ID   WP_000867712.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1020     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 877752..889050
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H77_RS04315 (I6H77_04315) rpsB 878577..879356 (+) 780 WP_000268475.1 30S ribosomal protein S2 -
  I6H77_RS04320 (I6H77_04320) tsf 879435..880475 (+) 1041 WP_000808057.1 translation elongation factor Ts -
  I6H77_RS04325 (I6H77_04325) cysK 880579..881505 (-) 927 WP_001029449.1 cysteine synthase A -
  I6H77_RS04330 (I6H77_04330) - 881602..882045 (-) 444 WP_000863903.1 PH domain-containing protein -
  I6H77_RS04335 (I6H77_04335) - 882060..882695 (-) 636 WP_000395765.1 YigZ family protein -
  I6H77_RS04340 (I6H77_04340) comFA/cflA 882752..884050 (+) 1299 WP_000867712.1 DEAD/DEAH box helicase Machinery gene
  I6H77_RS04345 (I6H77_04345) comFC/cflB 884047..884709 (+) 663 WP_000995723.1 ComF family protein Machinery gene
  I6H77_RS04350 (I6H77_04350) hpf 884789..885337 (+) 549 WP_000599114.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6H77_RS04355 (I6H77_04355) - 885419..886597 (+) 1179 WP_000656055.1 acetyl-CoA C-acetyltransferase -
  I6H77_RS04360 (I6H77_04360) - 886743..888716 (+) 1974 WP_000739979.1 DHH family phosphoesterase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49538.43 Da        Isoelectric Point: 8.1608

>NTDB_id=516471 I6H77_RS04340 WP_000867712.1 882752..884050(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1020]
MKVNPNYLGRLFTEKELTKEECQMAEKLPAMRKEKGKLFCQRCNSSILEEWHLPIGAYYCRECLLMKRVRSDQALYYFSQ
EDFPKQDVLKWRGQLTPFQEKLSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVIATTHQLLKFYHAFDLLIVDEVDAFPYVDNSMLYYAVKNSVKEDGLRIFLTATST
DELDRKVHTGELKRLSLPRRFHGNPLIIPKPVWLSDFNHCLEKSQLSSKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LKEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKQMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=516471 I6H77_RS04340 WP_000867712.1 882752..884050(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1020]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACAAAAGAAGAATGTCAGATGGCTGAGAA
ACTTCCAGCAATGAGAAAAGAGAAAGGGAAACTGTTTTGTCAACGTTGTAATAGTAGTATTCTAGAAGAATGGCATTTGC
CTATTGGTGCCTACTATTGTAGGGAGTGTTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCCTTATACTATTTTTCGCAG
GAAGATTTTCCAAAGCAAGATGTTCTCAAATGGCGTGGTCAGTTAACCCCTTTTCAGGAAAAGTTATCAGAGGGGTTGAT
TCGAGCAGTCGAAAAGAAAGAACCGACTTTAGTTCATGCTGTGACGGGTGCTGGAAAGACAGAGATGATTTATCAAGTTG
TAGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCAAGCCCTAGAATTGATGTATGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGTGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAATTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ATAACTCTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTAAGGATATTCCTTACAGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCACACAGGAGAATTAAAACGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCACTGTTTAGAGAAAAGTCAGTTGTCATCCAAGTTAAAGACCTACA
TTGAGAAACAGAGAAGAACAGGTTATCCTTTGCTGATTTTTGCATCAGAGATTAAAAAAGGCGAGAAACTAAAAGAAATC
TTGAAGGAGCAGTACCCGAATGAGAATATCGGATTTGTGTCTTCTGTCACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGTTTGATTCAGATTGGAGGGCGAGTTGGACGCAGTATGGATAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAAAAGGCAATCAAGGAAATCAAGCAGATGAA
TAAGGAGGCAGGGTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(291-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.046

100

0.9
  comFA/cflA Streptococcus mitis SK321

89.12

100

0.891
  comFA/cflA Streptococcus pneumoniae Rx1

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae D39

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae R6

88.657

100

0.887
  comFA/cflA Streptococcus pneumoniae TIGR4

88.426

100

0.884
  comFA Lactococcus lactis subsp. cremoris KW2

50.735

94.444

0.479
  comFA Latilactobacillus sakei subsp. sakei 23K

38.813

100

0.394