Detailed information NTG0516146

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: I6H76_RS07085
• Genome accession: NZ_CP065994
• Coordinates: 1376232..1376957 (+)
• Length: 241 a.a.
• NCBI ID: WP_006531891.1
• Uniprot ID: -
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1371232..1381957

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS07050 (I6H76_07050)	-	1371450..1371632 (+)	183	WP_006531883.1	Blp family class II bacteriocin	-
I6H76_RS07055 (I6H76_07055)	-	1372250..1372480 (+)	231	WP_043878356.1	bacteriocin	-
I6H76_RS07060 (I6H76_07060)	-	1372569..1372880 (+)	312	WP_003066586.1	hypothetical protein	-
I6H76_RS07065 (I6H76_07065)	-	1373094..1373186 (+)	93	Protein_1343	Blp family class II bacteriocin	-
I6H76_RS07070 (I6H76_07070)	-	1373244..1373648 (+)	405	WP_018364981.1	hypothetical protein	-
I6H76_RS07075 (I6H76_07075)	-	1373829..1374875 (+)	1047	WP_006531888.1	thioredoxin fold domain-containing protein	-
I6H76_RS07080 (I6H76_07080)	-	1375380..1376045 (+)	666	WP_006531890.1	DUF6261 family protein	-
I6H76_RS07085 (I6H76_07085)	comE/comE1	1376232..1376957 (+)	726	WP_006531891.1	LytTR family DNA-binding domain-containing protein	Regulator
I6H76_RS07090 (I6H76_07090)	-	1376970..1378289 (+)	1320	WP_006531892.1	sensor histidine kinase	-
I6H76_RS07095 (I6H76_07095)	-	1378310..1378459 (-)	150	WP_006531893.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I6H76_RS07110 (I6H76_07110)	rsgA	1379085..1379957 (+)	873	WP_006531894.1	ribosome small subunit-dependent GTPase A	-
I6H76_RS07115 (I6H76_07115)	rpe	1379964..1380626 (+)	663	WP_006531895.1	ribulose-phosphate 3-epimerase	-
I6H76_RS07120 (I6H76_07120)	-	1380619..1381251 (+)	633	WP_006531896.1	thiamine diphosphokinase	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 28006.97 Da
• Isoelectric Point: 5.2156

>NTDB_id=516146 I6H76_RS07085 WP_006531891.1 1376232..1376957(+) (comE/comE1) [Streptococcus infantarius strain FDAARGOS_1019]
MDIFVLEDDIPQQFRMERAINLVMESNNWHYRYLEISSNPDEIIAVAGNGEHQIFFLDLEIKGEEQQGIDVAKAIREKNS
TAIIVFVTTHSEFMLLTYQSLVGAIDFIDKGLNEEAFNERLFVCLKEAVKRQEGNFGEHSYLFHTPQAKVRVAYDDILFF
ETSPAPHRVILHTKNERTEFYATIAEVAKSDERLFRCHRSFVVNVDNIARFDMRYKLIYFEMGETCPVARAKVKLLQEKI
G

Nucleotide

• Length: 726 bp

>NTDB_id=516146 I6H76_RS07085 WP_006531891.1 1376232..1376957(+) (comE/comE1) [Streptococcus infantarius strain FDAARGOS_1019]
GTGGATATTTTTGTACTCGAAGATGATATTCCCCAACAATTCCGAATGGAGCGTGCTATTAATCTTGTGATGGAATCAAA
TAACTGGCATTATCGGTATTTGGAGATTTCATCTAATCCTGATGAAATCATCGCAGTAGCAGGTAATGGTGAACATCAAA
TTTTCTTTCTTGATTTAGAAATTAAAGGTGAAGAGCAGCAAGGGATTGATGTTGCTAAAGCTATTCGTGAAAAAAATAGC
ACAGCTATTATTGTTTTTGTGACGACACATTCTGAATTCATGCTCTTAACCTATCAATCTTTAGTAGGTGCTATTGACTT
TATTGACAAAGGATTAAACGAAGAAGCGTTTAATGAACGCTTATTCGTTTGTCTTAAAGAAGCTGTCAAACGCCAAGAGG
GAAACTTTGGTGAACATTCCTACTTGTTTCATACCCCACAAGCCAAAGTGCGGGTAGCTTATGATGATATTTTATTTTTT
GAAACGTCACCAGCACCTCATCGTGTTATTTTGCACACTAAGAACGAACGTACAGAATTTTATGCGACCATAGCAGAAGT
GGCAAAATCAGATGAACGTCTTTTTAGATGTCATCGTTCTTTTGTGGTTAACGTGGATAATATCGCTAGATTTGATATGA
GGTATAAGCTCATTTATTTTGAGATGGGAGAAACCTGTCCTGTAGCTAGGGCTAAGGTGAAATTATTACAGGAGAAAATT
GGATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-120)

• LytTr DNA-binding domain (LytTR) (150-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	66.245	98.34	0.651
comE/blpR	Streptococcus mutans UA159	46.091	100	0.465
comE/comE2	Streptococcus equinus JB1	44.167	99.585	0.44
comE/comE2	Streptococcus gordonii strain NCTC7865	35.06	100	0.365
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	35.06	100	0.365
agrA	Staphylococcus aureus N315	35.656	100	0.361