Detailed information NTG0516107

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: I6H76_RS00970
• Genome accession: NZ_CP065994
• Coordinates: 190476..191318 (+)
• Length: 280 a.a.
• NCBI ID: WP_006532134.1
• Uniprot ID: A0A380KNL1
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 185476..196318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS00945 (I6H76_00945)	-	186370..186603 (+)	234	WP_006532140.1	hypothetical protein	-
I6H76_RS00950 (I6H76_00950)	-	186678..188145 (+)	1468	Protein_192	tyrosine-type recombinase/integrase	-
I6H76_RS00955 (I6H76_00955)	ylqF	188234..189088 (+)	855	WP_043878372.1	ribosome biogenesis GTPase YlqF	-
I6H76_RS00960 (I6H76_00960)	-	189075..189854 (+)	780	WP_043878371.1	ribonuclease HII	-
I6H76_RS00965 (I6H76_00965)	-	189855..190406 (+)	552	WP_006532135.1	sugar O-acetyltransferase	-
I6H76_RS00970 (I6H76_00970)	dprA	190476..191318 (+)	843	WP_006532134.1	DNA-processing protein DprA	Machinery gene
I6H76_RS00975 (I6H76_00975)	topA	191413..193551 (+)	2139	WP_043878370.1	type I DNA topoisomerase	-
I6H76_RS00980 (I6H76_00980)	-	193639..194304 (+)	666	WP_006532132.1	SatD family protein	-
I6H76_RS00985 (I6H76_00985)	-	194304..195017 (+)	714	WP_006532131.1	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31175.06 Da
• Isoelectric Point: 9.1835

>NTDB_id=516107 I6H76_RS00970 WP_006532134.1 190476..191318(+) (dprA) [Streptococcus infantarius strain FDAARGOS_1019]
MNNFELFKLKQAGLTNHNILTILDYQKREKKSLSLRDMAVVSKCKNPILFIEKYKDLDSKTLRKVFNQYPSISILDDDYP
LELKHSYNPPVLLFYQGNIELLNRPKIAVVGARTATQTGTKSVQKIIKELGNQFVIVSGLARGIDTSAHISALKNGGATI
AVIGCGLDVYYPKENKQLQDYLRKNHLILSEYTAAEAPLKYHFPERNRIIAGLSQGVIVAEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCITSGLDVLSEYQL

Nucleotide

• Length: 843 bp

>NTDB_id=516107 I6H76_RS00970 WP_006532134.1 190476..191318(+) (dprA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAATAATTTTGAACTATTTAAATTAAAACAAGCAGGACTAACAAATCACAATATTCTAACCATTTTAGATTATCAAAA
GCGAGAGAAGAAATCTCTTTCCTTGCGCGATATGGCTGTGGTGTCCAAATGTAAGAATCCTATTTTATTTATAGAAAAAT
ACAAAGATTTGGATAGTAAAACTTTGCGAAAAGTCTTTAACCAATACCCTAGTATTTCAATACTAGATGACGACTATCCG
CTGGAATTAAAACACTCTTATAATCCGCCTGTTTTGCTTTTTTATCAAGGCAATATTGAGCTACTAAATCGTCCAAAAAT
TGCAGTAGTAGGAGCACGCACAGCCACACAGACAGGAACCAAGTCCGTTCAAAAAATTATCAAAGAACTTGGAAATCAAT
TCGTCATTGTCAGTGGCCTAGCTAGAGGAATCGATACCAGCGCACATATTTCAGCCCTAAAAAATGGCGGGGCGACAATA
GCAGTTATTGGCTGCGGTCTTGACGTCTATTATCCCAAAGAAAATAAACAGTTACAGGACTACCTTAGAAAAAATCATTT
GATTTTAAGTGAATACACAGCAGCAGAAGCGCCGCTAAAATACCATTTCCCAGAACGCAATCGCATTATCGCAGGGCTAT
CCCAAGGCGTCATAGTAGCAGAAGCTAAGTTGCGATCTGGCAGTTTAATTACTTGTGAGCGCGCTCTAGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGTAATATTTTGGACGGAAAATCTGACGGATGTCATCATTTAATCAAAGAGGGCGCAAAGTG
CATCACATCAGGCCTAGACGTCCTTTCAGAATACCAATTGTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: A0A380KNL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	73.571	100	0.736
dprA/cilB/dalA	Streptococcus mitis SK321	62.857	100	0.629
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.5	100	0.625
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.143	100	0.621
dprA	Lactococcus lactis subsp. cremoris KW2	60.072	99.286	0.596
dprA	Legionella pneumophila strain ERS1305867	38.567	100	0.404